Mercola disputes coverage of a trial reporting 17% higher prostate cancer risk among men taking 400 IU of vitamin E daily, arguing the trial used a synthetic, petrochemically derived form, and calls a study tying supplements to mortality in older women deeply flawed.
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Vitamin E
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Vitamins
Vitamin E may boost risk of prostate cancer
In a trial of 35,533 men followed 7 to 12 years, those given 400 IU of vitamin E daily were 17 percent more likely to develop prostate cancer; selenium alone was linked to a 9 percent increase. The trial tested one form of vitamin E, not all of them.
Vitamins
Vitamin C, E cut breast cancer recurrence and death risk
Among 2,264 breast cancer patients in the Life After Cancer Epidemiology cohort, frequent vitamin C and E use was linked to roughly 30% lower odds of recurrence and of death from any cause, while frequent use of combination carotenoids was tied to higher mortality.
Vitamins
Use of vitamin E associated with increased risk of prostate cancer (PR)
In SELECT, a trial of 35,533 men, those randomized to daily vitamin E supplements had a significantly increased risk of prostate cancer, JAMA reports. The trial's first report had found no risk reduction from vitamin E or selenium and a statistically nonsignificant rise with vitamin E.
Vitamins
Vitamin E helps type 1 diabetes
Twenty children with type 1 diabetes took 600 mg of vitamin E daily for three months; the oxidation marker malondialdehyde fell and glutathione rose. Metabolic measures did not improve. The authors conclude the vitamin eases oxidative stress in these patients.
Vitamins
Vitamin E prevents stroke-induced injury
Ohio State researchers report that alpha-tocotrienol, a form of vitamin E, clears oxidized glutathione that would otherwise kill neurons, and that oral supplementation helped prevent strokes and stroke-induced injury in rodents by raising MRP1 expression.
Vitamins
Vitamin E helps diminish a type of fatty liver disease in children (PR)
In an NIH-funded trial, 58% of children with nonalcoholic steatohepatitis no longer had it after 96 weeks on a specific form of vitamin E, against 41% on metformin and 28% on placebo. Vitamin E beat placebo largely by reducing enlargement and death of liver cells.
Vitamins
Not all types of vitamin E fight lung cancer
Rutgers researchers fed mice carrying transplanted lung cancer cells diets with different tocopherols and found delta-tocopherol inhibited tumor growth most strongly, gamma-tocopherol less so, and alpha-tocopherol not at all. Delta also cut oxidative DNA damage and promoted tumor cell death.
Vitamins
Antioxidants in pecans may reduce heart risk
A Loma Linda trial fed 16 adults meals with and without 3 ounces of pecans. Pecan meals doubled serum gamma-tocopherol at 8 hours and cut oxidized LDL cholesterol by 26 to 33%, which the researchers tie to less inflammation in the arteries.
Vitamins
Vitamin E may help you live longer
In a randomized trial of 10,837 Finnish participants over 65, vitamin E cut mortality by 24 percent among those aged 71 and older but made no difference at ages 65 to 70. The piece also notes the American Heart Association's 2004 warning that 400 IU a day or more can raise death risk.
Vitamins
Vitamin E may increase the life expectancy of restricted groups of men (PR)
In a Finnish trial of 10,837 participants, vitamin E did not affect mortality at ages 65 to 70 but cut it 24 percent from age 71. Among 2,284 men with above-median vitamin C intake who smoked under a pack a day it added two years, while 80 percent of the cohort saw no effect.
Vitamins
Vitamin E rich foods
A ranked table lists foods supplying at least 10% of the 15 mg daily vitamin E RDA, with milligrams and calories per standard serving. Fortified cereals, sunflower seeds, almonds, sunflower and cottonseed oils, hazelnuts and turnip greens lead the list.
Vitamins
High intake of dietary vitamin E may reduce dementia risk
Rotterdam researchers followed 5,395 people aged 55 and older for about a decade and found those in the highest third of dietary vitamin E intake were 25 percent less likely to develop dementia. Vitamin C, beta carotene and flavonoids showed no link once confounders were taken into account.
Vitamins
Antioxidants may help prevent breast cancer
An Indian study in the Asian Pacific Journal of Cancer Prevention measured plasma antioxidants in 225 women and found higher beta-carotene, vitamin E and vitamin C accompanying significantly lower breast cancer risk. Higher vitamin A levels went the other way, tracking with higher risk.
Vitamins
Vitamin E rich foods cut dementia risk
Among 5,395 Dutch adults aged 55 and over, those eating the most dietary vitamin E were 25 percent less likely to develop dementia over 9.6 years; vitamin C, beta carotene and flavonoids showed no link. Whether vitamin E itself lowered the risk remains unknown.
Vitamins
Serum vitamin E may protect against Alzheimer's disease
Following 232 dementia-free adults aged 80 and over for six years, Karolinska researchers found those in the top tertile for total vitamin E had about 45 percent lower Alzheimer's risk, and for tocotrienols 54 percent. Among individual forms, only beta-tocopherol stood out.
Supplements
Vitamin C, E, Omega 3-fatty acids prevent pancreatic cancer
In a San Francisco Bay Area case-control study, the highest intakes of vitamins C and E were tied to 31 and 33 percent lower pancreatic cancer risk and omega-3s to 53 percent lower, while high saturated fat intake was tied to 60 to 160 percent higher risk. Vitamins from food showed no link.
Nutrition
Vitamin E may boost immune response triggered by flu vaccine
Japanese researchers measured immune response in 153 nursing home residents averaging 84.4 years and 95 health workers, before and after trivalent flu vaccination. Among the elderly, only vitamin E tracked significantly with response to A/H1N1 and B, suggesting it may help maintain that response.
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