Friday Nov 09. 2016 (foodconsumer.org) -- Vitamin D deficiency has been known to be implicated in the pathogenesis of Crohn's disease.  A new study in Inflammatory Bowel Diseases indicates that supplementation with high doses of vitamin D help Crohn's disease.In the study, 34 patients with Crohn's disease in remission were assigned to receive either 10,000 IU or 1,000 IU of vitamin D3 daily.The study finds that the high-dose vitamin D3 supplementation significantly improved 25-hydroxy-vitamin D levels.  The high-dose vitamin D3 supplementation also reduced the risk of relapse of Crohn's disease during the intervention.Vitamin D3 supplementation in both dosages improved depression and resulted in a good safety profile.Narula, Neeraj; Cooray, Mohan; Anglin, Rebecca; Marshall, John,  Impact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-Blind Controlled Study, Inflammatory Bowel Diseases, March 2016, doi: 10.1097/01.MIB.0000480168.31416.a6