A Journal of Clinical Oncology study of 1,601 BRCA1/2 carriers found those ever exposed to chest x-rays were 54 percent more likely to develop breast cancer, with the increase near 100 percent for exposure before 40. The study measured chest x-rays, not mammography itself.
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Disease
Breast cancer news: Breast milk may spread viruses that cause breast cancer
A study by W.K. Glenn and colleagues in BMC Research Notes found high-risk HPV and Epstein-Barr virus in human breast milk, raising the prospect of passing them to babies. An editor's note stresses breastfeeding's benefits outweigh its risks and that the HPV link is unsubstantiated.
Vitamins
Folate fights breast cancer?
In the Shanghai Women's Health Study, premenopausal women in the top quintile of folate intake were 48 percent less likely to develop breast cancer than those in the lowest. The highest niacin intake, by contrast, matched a 62 percent higher risk of ER+/PR+ disease.
Phytochemicals
Red grape polyphenols fight breast cancer
Resveratrol, quercetin and catechin each did nothing to breast cancer cells at 0.5 microM, but combined they cut cell proliferation and blocked the cell cycle, and they shrank tumours in a nude mouse model, with the strongest effect at 5 mg/kg.
Supplements
High carotenoid intake linked to lower risk for breast cancer
Pooling 18 cohorts covering over a million women and 33,380 breast cancers, researchers found the highest intakes of alpha-carotene, beta-carotene and lutein/zeaxanthin went with 13-16% lower risk of ER-negative breast cancer. Beta-cryptoxanthin tracked with lower risk of both types.
Disease
Diabetes, overweight linked to high risk of breast cancer
A Uruguayan study of 367 breast cancer cases and 545 controls found women with a history of diabetes were 64 percent more likely to have the disease, rising to 92 percent after menopause. Postmenopausal women with diabetes, overweight and dyslipidemia were more than nine times as likely.
Lifestyle
Cancer News: Induced abortion boosts breast cancer risk - new study
A case-control study from Nanjing reported that premenopausal women with three or more induced abortions were 141% more likely to develop breast cancer, a 55% increase after adjustment for other factors. Spontaneous abortion showed no such association.
Cancer
What type of diet may help prevent breast cancer?
In the Italian arm of the EPIC study, women eating a high glycemic load diet were 45% more likely to be diagnosed with breast cancer than those on a low glycemic load diet. The authors suggest heavy carbohydrate loads raise insulin-like growth factor, but studies are not all consistent.
Vitamins
Breaking cancer news: Dietary vitamin D fights breast cancer
Mice with MCF-7 breast cancer xenografts fed 5,000 IU/kg of ordinary vitamin D3 showed significant tumor shrinkage in more than half of cases, matching the effect of injected calcitriol without the side effects the active form produced.
Cancer
Drinking alcohol even in moderation boosts risk of breast cancer
European researchers pooled more than 100 studies and found up to one drink a day raised women's breast cancer risk by 4 percent, with three or more daily drinks raising it 40 to 50 percent. The authors advise women not to exceed one drink a day.
Environment
Preservative in consmetics may cause breast cancer
A Journal of Applied Toxicology study measured paraben esters in tissue from 40 mastectomies and found at least one in 158 of 160 samples. The authors note no causal link to breast cancer has been established, but parabens act like estrogen, which is known to promote breast carcinogenesis.
Cancer
This Popular Nut Slashed Breast Cancer Risk in Mice by 50%
Mercola reports the FDA warned Diamond Food that citing peer-reviewed research on the omega-3 fats in walnuts would make the nuts "new drugs" needing approval, and urges support for the Free Speech about Science Act (HR 1364), which would let producers cite legitimate studies.
Drug
Radiotherapy for Hodgkin lymphoma can cause breast cancer
Women given chest wall radiation for Hodgkin lymphoma ran a 25 percent higher risk of later breast cancer over a decade of follow-up. Among women carrying the FGFR2-related variant rs12119648, those treated with radiation plus chemotherapy were 59 percent more likely to develop breast cancer.
Cancer
Your Greatest Weapon Against Breast Cancer (Not Mammograms)
Mercola argues against routine mammograms, saying the Institute of Medicine now acknowledges mammogram radiation as a factor in breast cancer, citing false positive rates up to six percent, and pointing to research that 30 percent of breast tumours go away on their own.
Cancer
Can Moderate Drinking Boost Breast Cancer Risk?
A JAMA study of 105,986 women in the Nurses' Health Study linked 3 to 6 drinks a week to a 15 percent higher risk of invasive breast cancer. The authors call it a small increase, tied most consistently to cumulative alcohol intake across adult life.
Disease
Older menopausal women with hormone-receptor-positive breast cancer more likely to die - study
A JAMA study of 9,766 patients in the TEAM trial found women diagnosed with hormone receptor-positive breast cancer at 65 to 74 were 25 percent more likely to die of it than those diagnosed before 65, and those 75 or older were 63 percent more likely.
Environment
Estrogenic cosmetic chemicals - parabens found in breast cancer tissue
British researchers found one or more parabens in 158 of 160 breast tissue samples taken from 40 mastectomy patients, including seven women who said they had never used underarm products. Levels were four times higher than in a similar 2004 study.
Food
Red wine may be safer than white wine
In a study of 36 women, drinking about 8 ounces of red wine daily shifted sex hormone levels in a way that resembles aromatase inhibitor drugs, while white wine did not. The piece notes alcohol itself is a recognized human carcinogen tied to breast cancer risk.
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