Two studies tie insulin-like growth factor I to breast cancer: French researchers measured higher average serum IGF-I in 44 patients than in 92 controls, 26 versus 20 ng/ml, and a second found top-quartile women 92 percent more likely to be diagnosed, an association seen only in Caucasian women.
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Cancer
Diet, lifestyle and cancer risk, prevention and treatment.
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Cancer
Soft drinks boost pancreatic cancer risk - study
A Nature study timed pancreatic cancer at an average 11.7 years to the first cancer cell, 6.8 more years before it can spread and 2.7 years to kill, suggesting a window for prevention. A Singapore cohort study found people drinking two or more soft drinks a week had an 87 percent higher risk.
Cancer
Pancreatic cancer, linked to dietary habits, grows slowly - studies
Johns Hopkins researchers modelling mutations from patients who died of pancreatic cancer estimate about 11.7 years for the first cancer cell to arise in a high-grade lesion, 6.8 more years before spread, and 2.7 years to death, leaving a window for earlier detection.
Cancer
HRT Linked to Breast Cancer Death Risk
A study reported in the Journal of the American Medical Association found women assigned to hormone replacement therapy were twice as likely to die of breast cancer as those on placebo, contradicting the belief that HRT-linked tumors are easier to treat.
Cancer
How Does Induced Abortion Raise Breast Cancer Risk?
Surgeon Angela Lanfranchi contributes a piece arguing that growing evidence ties induced abortion, though not miscarriage, to higher breast cancer risk. She stresses it is one factor among many: most women with breast cancer never had an abortion, and most who have had one never get it.
Cancer
Breast Cancer: Breast Reconstruction Following Mastectomy
The piece walks through breast reconstruction after mastectomy: a plastic surgeon replaces skin, breast tissue and nipple, with symmetry between the breasts as the goal. It stresses the choice need not be made at the time of surgery and is not cosmetic surgery.
Cancer
J&J Drug Provides Hope to Prostate Cancer Patients
In a Phase III trial of men with advanced prostate cancer who had already had other treatment, those given abiraterone with a low-dose steroid lived 14.8 months against 10.9 on placebo. Lead investigator Johan de Bono noted only four drugs have ever shown a survival benefit in the disease.
Cancer
What to Tell Your Daughter About Breast Cancer
Four suggestions for mothers during Breast Cancer Awareness Month: teach a daughter how her breasts normally feel and to examine them monthly after 20, share family history with her doctor, book a gynecologic exam once she is sexually active, and keep up with mammograms.
Cancer
Pink Alert: Genetic Discrimination with BRCA1 or BRCA2 Positive Gene
The 2008 Genetic Information Nondiscrimination Act bars genetic discrimination in health insurance and employment, but leaves out life, disability and long-term care insurance, where insurers can request medical records and weigh BRCA test results when deciding coverage.
Cancer
Eating fish lowers risk of dying from prostate cancer
Reviewing 17 case-control and 14 cohort studies, Konrad Szymanski's team found no link between eating fish and getting prostate cancer, but heavy fish eaters were 44 percent less likely to develop metastatic disease and up to 63 percent less likely to die of it.
Cancer
Pink Alert: Does Gasoline Increase Breast Cancer Risk in Men?
In the largest study of men diagnosed with breast cancer, Danish researchers found significantly higher rates among men who spent 10 years or more in jobs exposed to gasoline fumes and combustion, with the strongest effect in those who started before 40. Benzene is implicated.
Cancer
Pink Not Just for Women, Men Die From Breast Cancer, too
The American Cancer Society estimates 1,970 men will be diagnosed with invasive breast cancer and about 390 will die of it, a lifetime risk of roughly 1 in 1,000. Recent studies suggest men and women diagnosed at the same stage have equal survival prospects.
Cancer
Pink news: Plastic chemical may promote breast cancer development
A study in Environmental Health Perspectives found low nanomolar concentrations of bisphenol A blunted the effect of the chemotherapy drugs doxorubicin, cisplatin and vinblastine in two breast cancer cell lines, independent of the classical estrogen receptors. The work was done in cultured cells.
Cancer
Pink tips: How to prevent breast cancer
The writer walks through the American Cancer Society's breast cancer risk factors, separating unmodifiable ones such as gender, age and BRCA mutations from modifiable ones such as alcohol, obesity, inactivity and hormone use, and argues diet and lifestyle can still influence genetic risk.
Cancer
Pediatric Cancer: A Cure for Neuroblastoma?
About 650 US children a year are diagnosed with neuroblastoma, and nearly half have a high-risk form with poor survival. In a randomized phase III Children's Oncology Group trial, a new immunotherapy raised the share alive and progression-free at two years above the 46 percent on standard care.
Cancer
Breast Cancer Awareness Month, Physical Activity, Depression, Healthcare Reform
A study in Cancer analysed 1,162,596 Danish men and found those whose wives or girlfriends were diagnosed with breast cancer were 309 percent more likely to be hospitalized for a mood disorder such as major depression, suggesting male partners need emotional and social support.
Cancer
Pediatric Cancer:Curing the Beast
An appeal about childhood cancer that lists the types, from leukemia and lymphoma to neuroblastoma and Wilms' tumor, and relays parents' accounts of a son, Sam, dying in their arms and of a daughter's leukemia diagnosis after what looked like flu.
Cancer
Scientists Make Progress in Understanding Ovarian Cancer Risk
Analyzing DNA from more than 10,000 women with ovarian cancer and 13,000 without, researchers report in Nature Genetics five genetic variants tied to ovarian cancer risk, on chromosomes 2, 3, 8, 17 and 19. Four of the five were more common in women with serous ovarian cancer.
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