An Oxford-led study in Genome Research found vitamin D receptor binding sites clustered near genes tied to multiple sclerosis, Crohn's disease, lupus, rheumatoid arthritis, colorectal cancer and chronic lymphocytic leukemia, and traced direct interaction in 200 genes.
Section archive
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Cancer
Diet, lifestyle and cancer risk, prevention and treatment.
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Cancer
Dodging Colorectal Cancer Under 40
The American Cancer Society estimated about 102,900 new colon cancers, 39,670 rectal cancers and 51,370 deaths in the United States for 2010, with death rates falling for 15 years as screening finds and removes polyps before they turn cancerous.
Miscellaneous
The Medical Scandal that’s Robbing Cancer Patients of Their Right to Life
Dr. Mercola retells Dallas News reporting on Leah Siegel, diagnosed with stage four breast cancer in 2008 and given two to three years. Her husband says doctors jumped from drug to drug with no real plan, and one cocktail left her with blistered hands and sores that stopped her eating.
Cancer
Breast Cancer Risk: One Size May Not Fit All
USC researchers tracking 3,000 women from 1995 to 2006 found 15 years or more of estrogen therapy raised breast cancer risk 19%, and estrogen with progestin raised it 83%. Thinner women faced greater post-HRT risk than obese women, which the team did not explain.
Food
Fructose promotes growth of pancreatic cancer
UCLA researchers compared how pancreatic cancer cells in Petri dishes use glucose and fructose, and found the cells route fructose through the non-oxidative pentose phosphate pathway to build nucleic acids for division. Lead author Anthony Heaney calls refined sugar a hidden danger.
Watch-List
New Warning About Excessive “Agent Orange” Toxin in Baby Formula and Breast Milk
Dr. Mercola writes that as the EPA reviews a proposed safe exposure limit for dioxin, research indicates a nursing infant takes in 77 times that amount and adults 1,200 times. Dioxin is a byproduct of incineration, smelting, chlorine bleaching and pesticide making, and builds up in animal fat.
Cancer
American Cancer Society Site Improved
The American Cancer Society rebuilt cancer.org, which draws 23 million visitors a year, with new search and navigation. The site is now organized into Learn About Cancer, Stay Healthy, Find Support & Treatment, Explore Research and Get Involved sections.
Cancer
Omega-3's Reduce Your Risk of Breast Cancer
Among more than 35,000 postmenopausal women surveyed about supplement use, regular fish oil users had a 32 percent lower risk of breast cancer. The reduction appeared limited to invasive ductal breast cancer; other specialty supplements showed no link.
Cancer
FDA to Determine Avastin's Fate
An FDA oncology panel meets July 20 to weigh whether Avastin keeps its breast cancer indication. The 2008 study behind its accelerated approval showed 5.5 extra months before the disease worsened; later research put the gain at 1 to 2.9 months.
Cancer
HPV and Skin Cancer: Facts and Figures
Dartmouth's Margaret Karagas found that testing positive for two or three strains of HPV was associated with a 44 percent higher risk of squamous cell carcinoma, while stressing the link may not be causal. The study compared 663 patients with SCC, 898 with basal cell carcinoma and 805 controls.
Cancer
Enhanced Milieu Key to Cancer Survival
Ohio State researchers found mice housed in large cages with 18 to 22 others, toys and running wheels developed tumors later and had lesions 43 percent smaller than mice in standard cages. The enriched mice also showed a 90 percent drop in leptin.
Cancer
Fish Oil, Breast Cancer and Other Interesting Facts
Among 35,000 postmenopausal women followed six years, taking fish oil four to seven times a week was associated with a 32 percent lower breast cancer risk. Lead author Emily White cautions that the correlation does not prove cause and that more research is needed.
Cancer
OH Woman Knows Value of Breast Cancer Screening
An Ohio woman with a long history of benign breast cysts found a cancerous tumor the size of a tangerine about three months after a negative mammogram. CDC data show screening has leveled off, 81.1 percent in 2008 against 81.5 percent in 2006, lowest among women aged 50 to 59.
Cancer
Roche Seeks Approval for Breast Cancer Drug
Roche has asked the FDA to approve trastuzumab-DM1 for advanced HER2-positive breast cancer, the first conjugated monoclonal antibody the agency will review. Based on Phase II results, a launch could come as early as 2011, with Phase III studies still to run.
Cancer
Mediterranean diet cuts prostate cancer risk
Reviewing evidence in Molecular Nutrition and Food Research, Itsiopoulos and University of Melbourne colleagues note that Greek men in Greece and in Australia die of prostate cancer less often than men in many Western countries, and suggest the Mediterranean diet may explain the gap.
Cancer
Swedish Study: PSA Screening Saves Lives
A University of Gothenburg study followed 20,000 men for 14 years and found prostate cancer deaths were half as high among those offered PSA screening. Critics point to overdiagnosis: one US study found that for every 20 men treated, only one benefits from early screening.
Cancer
Study: Soy and Brazil nuts fight prostate cancer
Genistein from soy and selenium from Brazil nuts, separately and together, slowed the growth of both hormone-dependent and hormone-independent prostate cancer cells and cut MMP-2 expression, with the combination most effective. Healthy prostate cells were unaffected.
Cancer
HRT Under Scrutiny
The US Supreme Court let a new trial proceed for Donna Scroggin, who developed breast cancer after 11 years on Provera, Premarin and Prempro. A 2008 jury awarded her $27 million in punitive and $2.7 million in compensatory damages; Wyeth faces more than 8,000 suits.
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