In the medical records of 5.24 million UK patients, 17 of the 22 cancers assessed were positively associated with higher body mass index, among them cancers of the uterus, gallbladder, kidney, cervix, thyroid, liver, colon and ovary.
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Cancer
Diet, lifestyle and cancer risk, prevention and treatment.
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Cancer
Egg eaters at higher risk for ovarian cancer
A Chinese meta-analysis of 12 studies found women eating the most eggs were 20 percent more likely to develop ovarian cancer. The link was significant in case-control but not cohort studies, and the authors say larger cohorts are needed; the data do not show cause.
Cancer
Vitamin D prevents breast cancer
A case-control study of 60 Iranian women with newly diagnosed breast cancer and 116 healthy women found those whose clothing fully blocked sunlight were 10 times likelier to have the disease. Half the subjects were severely vitamin D deficient. The design cannot establish cause.
Cancer
Weight loss may reverse basal-like breast cancer ***
In obese mice bred to develop mammary tumours, switching from a high-fat to a low-fat diet just before tumour onset reversed tumour progression. Weight loss blunted the HGF/c-Met pathway and lowered insulin and the leptin-to-adiponectin ratio.
Cancer
High Cholesterol Increases Risk of Breast Cancer
Researchers followed 664,159 women in the UK and found breast cancer risk 64 percent higher among those with high cholesterol, according to a report presented at a cardiovascular biology meeting in Barcelona. The work builds on earlier research linking obesity to breast cancer risk.
Cancer
Researchers Issue Stronger Guidelines for Preventing Cancer
Writing in the Journal of the American College of Nutrition, researchers apply the precautionary principle to diet and cancer, advising people to limit or avoid alcohol, dairy, red and processed meat and high-temperature-cooked meats, and to eat more soy, fruit and vegetables.
Cancer
High testosterone boosts risk of breast cancer? - news with opinion
A case-control study in the Journal of the National Cancer Institute put premenopausal women in the top quartile for serum testosterone at 73 percent higher odds of breast cancer. The writer objects that no estrogen data was reported and points to contrary evidence.
Cancer
Vitamin C increases odds of breast cancer survival
A European Journal of Cancer meta-analysis of 10 articles covering 17,696 breast cancer cases found post-diagnosis vitamin C supplement use was associated with 19 percent lower all-cause mortality and 15 percent lower breast cancer mortality.
Cancer
Vitamin D inhibits oral cancer growth
In three oral cancer cell lines, 1,25-dihydroxyvitamin D3 at 100 nmol inhibited growth by 19.7% in CAL27 and 43.6% in SCC25, cut cell viability and activated the caspase and bcl:bax pathways. This was laboratory work, not a trial in patients.
Cancer
Calcium supplements prevent colorectal cancer
A dose-response meta-analysis found each extra 300 mg of total calcium a day was associated with an 8% lower colorectal cancer risk across 15 studies, and each 300 mg of supplemental calcium with a 9% lower risk in six studies.
Cancer
High cholesterol inked to high risk of breast cancer
A Science report finds 27-hydroxycholesterol, a cholesterol metabolite, increases estrogen-receptor-dependent breast tumor growth and metastasis in mouse models, suggesting that lowering cholesterol or blocking the CYP27A1 enzyme may help.
Cancer
Research studies show mango may help prevent breast cancer
Texas A&M's Susanne Talcott ran one cell-culture study and one mouse study testing whether the polyphenols in mango carry the anti-inflammatory and cell-toxicity properties that earlier work attributed to such compounds.
Cancer
Protein, Fat, and Dairy Linked to Prostate Cancer
Research presented to the American Urological Association analyzed diets of almost 10,000 men: a high-carbohydrate, low-protein, low-fat pattern went with 60-70% lower prostate cancer risk and a fiber-rich diet with 70-80% lower. Milk tracked with advanced disease.
Cancer
Spirulina may prevent sin cancer - study
Kobe University researchers report that dietary spirulina platensis lowered skin cancer risk in both repair-enzyme-deficient and normal mice exposed to UV, suppressing tumour induction and development. They credit anti-inflammatory and antioxidant effects. The work used mice only.
Cancer
Spirulina prevents breast cancer - study
In rats given the carcinogen DMBA, spirulina supplementation cut mammary tumor rates from 87 percent to 13 percent, according to The American Journal of Pathology. Lab tests showed it slowed cell proliferation and triggered apoptosis by raising Bax and lowering Bcl-2.
Cancer
Milk, cheese, but not yogurt linked to liver cancer
In an EPIC cohort of 477,206 adults followed about 11 years, the highest consumers of total dairy, milk and cheese were 66%, 51% and 56% more likely to develop liver cancer than the lowest. Yogurt showed no association, nor did the same nutrients from non-dairy sources.
Cancer
Genes Elevate Existing Risk Associated with Processed Meat and Cancer
Pooling 9,287 colorectal cancer cases and 9,120 controls from 10 studies, researchers found risk rose 15% with red meat and 11% with processed meat, climbing to 20% and 39% in carriers of two genetic variants. Fruit, vegetables and fiber tracked with lower risk.
Cancer
High sexual activity linked to high prostate cancer risk - study
A meta-analysis by Dennis and Dawson in Epidemiology found men with a history of sexually transmitted infection were 40% more likely to develop prostate cancer, and those who had syphilis 130% more likely. Frequent sexual activity carried 20% higher risk.
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