An Indiana hospital fired eight employees, including three veteran nurses, who refused mandatory flu shots; about 1,400 of its 20,000 staff declined. The writer argues flu vaccine efficacy rarely exceeds 50% and cannot keep viruses out of hospitals.
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Disease
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Disease
Overweight, obese Americans live longer than those with normal weight? Why?
A commentary questioning the meta-analysis of nearly 100 studies that found overweight and grade 1 obesity carried lower mortality than normal weight. It notes Americans carry higher BMIs than the Japanese yet live shorter lives, and invites readers to send in explanations.
Disease
Type 2 diabetes mellitus linked to acute pancreatitis
A meta-analysis of seven observational studies covering more than 15 million people, published in the European Journal of Gastroenterology and Hepatology, found people with type 2 diabetes were 84 percent more likely to develop acute pancreatitis than those without it.
Disease
Abdominal obesity during adulthood linked to liver cancer, gallbladder cancer
Among 359,525 people in the EPIC study, those in the highest third of waist-to-hip ratio were 3.5 times as likely to develop liver cancer as those in the lowest third. The greatest weight gain during adulthood carried 2.48 times the risk of hepatocellular carcinoma.
Disease
Renal dysfunction linked to stroke after coronary artery bypass grafting
Among 29,057 Swedish bypass patients in the SWEDEHEART registry, those with lower glomerular filtration rates faced 17% to 79% higher stroke risk than patients with normal kidney function. Hemorrhagic stroke risk rose more steeply than ischemic stroke risk.
Disease
Celiac disease linked to type 1 diabetes
A study in Endocrine covering 492 type 1 diabetes patients in Western Sicily found 4.5% had already been diagnosed with celiac disease, against a reported general Italian prevalence of 1 in 1,000. Celiac disease was usually diagnosed at or after the diabetes diagnosis.
Disease
“American Gut” - One of the Most Important Health Projects of the 21st Century
Mercola promotes the American Gut Project, in which University of Colorado researchers and collaborators let participants learn which microbes inhabit their intestines. Co-founder Jeff Leach says the team hopes to inform what diet people should follow; the data will be made public.
Disease
Triple negative early stage breast cancer poses similar death risk as other types
Among 446 breast cancer patients followed about 78 months in Korea, researchers found no difference in survival between triple negative early stage disease and other types, with 33 deaths and 40 distant metastases recorded. The study appeared in Radiation Oncology.
Disease
News on Viruses and viral diseases: Human papillomavirus infection less likely in circumcised men
A review of 21 studies covering 8,046 circumcised and 6,336 uncircumcised men found circumcision associated with 43 percent lower genital HPV prevalence, and 33 percent lower high-risk HPV in two randomised trials. It was not linked to HPV acquisition, clearance or genital warts.
Disease
Risk factors for early death after lung cancer surgery
Among 12,096 English patients who had curative surgery for non-small cell lung cancer, 3 percent died within 30 days and 6 percent within 90. Age and surgery type mattered most: pneumonectomy patients were three times as likely as lobectomy patients to die within 30 days.
Disease
Risk factors for sudden cardiac death in postmenopausal women
Drawing on 161,808 Women's Health Initiative participants, researchers put sudden cardiac death at 2.4 per 10,000 women a year and tied it to higher pulse, waist-to-hip ratio, white cell count and heart failure. Nearly half of those who died had known coronary disease.
Disease
Breast cancer patients likely to suffer sexual dysfunction
A study in Support Care Cancer found 64% of breast cancer patients aged 45 or younger reported a sexual dysfunction during treatment, falling to 45% afterwards. Early menopause and hormone therapy were linked to arousal problems, and most affected women never raised it with a clinician.
Disease
Periodontitis linked to obstructive sleep apnea
Among 687 Korean adults aged 47 to 77, obstructive sleep apnea was associated with an 84 percent higher risk of periodontitis, rising to 151 percent among those 55 and older. The authors say the causal relationship between the two still needs to be clarified.
Disease
Myocardial infarction plus diabetes mellitus leads to high sudden cardiac death risk
Among 610 heart attack survivors enrolled in cardiac rehabilitation, the 236 with diabetes died more often over five years and faced a substantially higher risk of sudden cardiac death than those without, even when they showed no clinical sign of residual myocardial ischemia.
Disease
Diabetes mellitus type 2, metabolic syndrome linked to flame retardant exposure
Analyzing 1,367 adults from NHANES 2003-2004, Korean researchers found those most exposed to the flame retardants PBB-153 or PBDE-153 were more than twice as likely to have type 2 diabetes as the least exposed. Highest PBB-153 exposure tracked with nearly triple the metabolic syndrome risk.
Disease
What is Asperger syndrome?
A primer on Asperger syndrome, a milder form of autism spectrum disorder in which people usually keep normal language and intellectual ability but struggle socially. A Swedish study put prevalence between 4.1 and 7.1 per 1,000 children aged 7 to 16, depending on method.
Disease
Uric acid linked to deaths from all causes in diabetes, coronary artery disease
Among 3,705 patients with type 2 diabetes and angiography-confirmed coronary artery disease followed for a year, 14 percent in the highest uric acid quartile died, against about 5 percent in the lower three. After adjustment, the highest quartile carried a 25 percent higher risk.
Disease
HIV/AIDS Update - December 1 - World AIDS Day
An FDA World AIDS Day update counts 36 approved HIV/AIDS therapies and highlights four 2012 advances: Truvada for prevention, the OraQuick In-Home HIV test, the four-drug single tablet Stribild, and more than 150 antiretrovirals cleared for use under PEPFAR.
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