Mercola cites a Journal of the National Cancer Institute study finding Swedish county mortality data consistent with limited or no effect of mammography screening on breast cancer deaths in women aged 40 to 69. Its lead author urges franker talk about overdiagnosis and overtreatment.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
Radical prostatectomy no better observation in reducing death from localized prostate cancer
Among 731 men with localized prostate cancer randomly assigned to radical prostatectomy or observation, 47.0 percent of surgery patients and 49.9 percent of observation patients died over a median 10 years. Surgery caused adverse events in 21.4 percent within 30 days, including one death.
Drug
Mounting Evidence Shows Many Vaccines are Ineffective and Contribute to Rise of Outbreaks Caused by Mutated Viruses
Research published in March found 81 percent of 2010 California whooping cough cases in people under 18 occurred in those fully up to date on the vaccine, and only 8 percent in the unvaccinated, which Mercola says undercuts blaming parents who file exemptions.
Drug
Ovarian Cancer Screening Does More Harm Than Good
JAMA reports the US Preventive Services Task Force upheld its position that transvaginal ultrasound and CA-125 testing do more harm than good as ovarian cancer screens in symptom-free women at average risk. Gynecologic oncologists welcomed the grade D recommendation.
Drug
Top Ten Reasons to Avoid Your Doctor
Mercola argues most doctor visits end in prescriptions that suppress symptoms instead of addressing causes. His first example is the annual Pap smear, which the US Preventive Services Task Force now advises against in favor of screening every three years from age 21 to about 65.
Drug
Pharmaceutical Drugs are 62,000 Times More Likely to Kill You than Supplements
Citing data compiled by the Alliance for Natural Health International, Mercola reports that adverse reactions to pharmaceutical drugs are 62,000 times more likely to kill you than food supplements and 7,750 times more likely than herbal remedies.
Drug
Double-Whammy! Doctors Demonize Vaccine Choices as FDA Licenses New Combo Vaccine
A Pediatrics study by CDC and Oregon Health Authority researchers found about 10 percent of Portland parents give their babies fewer vaccines than the CDC schedule calls for. The article accuses doctors of demonizing those parents and questions FDA's licensing of GSK's MenHibrix.
Drug
HIV/AIDS Update -More than 150 antiretroviral drugs available through PEPFAR for worldwide HIV/AIDS relief
FDA has approved or tentatively approved 152 antiretroviral drugs for use through PEPFAR. Tentative approval means a product met manufacturing, safety and efficacy requirements but cannot be marketed in the US because of patents or exclusivity, though it can be bought abroad.
Drug
Prostate cancer news: Prostate cancer screening does not save lives
Danish researchers report in Acta Oncologica that prostate cancer incidence rose from 29.2 to 76.2 per 100,000 person-years between 1978 and 2009, while mortality held at 19 per 100,000 throughout — more cases diagnosed, no change in deaths.
Drug
Why Did the Wall Street Journal Bury the Merck Fraud Story?
Mercola asks why the Wall Street Journal pulled its June 22, 2012 story on a whistleblower suit accusing Merck of falsifying mumps vaccine efficacy data. The link went dead and the piece vanished from archives; he says the Journal has not answered his team.
Drug
FDA Okays weight loss drug Qsymia, would you take it?
The FDA cleared Vivus's Qsymia, a phentermine and topiramate combination, on July 17 for obese adults or overweight adults with a weight-related condition, to be used alongside a reduced-calorie diet and exercise. Women who may become pregnant should not take it.
Drug
HIV News: FDA Okays old drug for HIV prevention, but would you take it?
The FDA approved Truvada for pre-exposure prophylaxis, its first such approval, based on two trials: iPrEx cut infection risk 42% in 2,499 high-risk men and transgender women, and Partners PrEP cut it 75% among 4,758 serodiscordant couples. Efficacy tracked adherence.
Drug
FDA approves Afinitor for advanced breast cancer
The FDA approved everolimus, sold as Afinitor, with Aromasin for postmenopausal women whose hormone receptor-positive, HER2-negative breast cancer progressed after letrozole or anastrozole. In a 724-patient trial the pair added 4.6 months of progression-free survival over Aromasin alone.
Drug
Once-Weekly Glucose-Lowering Therapy for Type 2 Diabetes
A Clinical Diabetes report says once-weekly exenatide, a GLP-1 receptor agonist, lowered A1C by 1.3 to 1.9 percent and body weight by 2 to 4 kg with minimal hypoglycemia risk absent a sulfonylurea. Injection-site and gastrointestinal effects eased over time, and the gains held for three years.
Drug
Cannabinoids: novel breast cancer therapy?
Spanish researchers reviewing a decade of laboratory work report that cannabinoids curb proliferation, migration and invasion in cultured cancer cells and suppress tumor growth and metastasis in mouse models, and suggest cannabinoid-based medicines may help most breast tumor subtypes.
Drug
Old men should not receive prostate cancer screening - medical group advises
ASCO recommends in the Journal of Clinical Oncology that men with a life expectancy of 10 years or less be discouraged from general PSA screening, saying the evidence is strong that harms from unnecessary biopsy, surgery or radiation outweigh the benefits.
Drug
HIV prevention drug is now available. Would you risk your life to use it?
The FDA approved Truvada for use by healthy people at high risk of HIV. Trials showed transmission fell more than 40% among men who have sex with men and more than 70% in couples with one infected partner; officials stress it is not a stand-alone measure.
Drug
This Inaccurate (But Popular) Test Could Cause Months of Unnecessary Stress and Trauma
Mercola cites the 2009 U.S. Preventive Services Task Force decision against routine mammograms for women under 50, a Norwegian study finding as many as 1 in 4 women overdiagnosed, and New York Times reporting on FDA surveillance of agency whistleblowers.
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