Dr. Eugene Carragee of Stanford told a spinal surgeons' conference that patients who received Medtronic's Infuse bone-growth protein had 2.5 times the risk of pancreatic, breast and prostate cancers. The Spine Journal flagged cancer and other harms in June.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
FDA approves Xarelto to prevent stroke in people with common type of abnormal heart rhythm
FDA approved the anti-clotting drug Xarelto (rivaroxaban) to reduce stroke risk in people with non-valvular atrial fibrillation, a rhythm disorder affecting more than 2 million Americans in which blood pools in the upper heart chambers and can clot.
Drug
If You're Taking This Drug - Don't Take Aspirin
Mercola cites an analysis finding that combining aspirin with antidepressants may raise the risk of abnormal bleeding by 42 percent, and argues that newer research undercuts the chemical-imbalance and low-serotonin theories behind current depression drugs.
Drug
20 TIMES the Risk of Autism When You Make This Choice...
Dr. Mercola cites a survey comparing vaccinated and unvaccinated children that reported higher rates of allergies, asthma, ADHD, ear infections and autism among the vaccinated, and argues the full childhood schedule has never been tested for long-term safety in prospective trials.
Drug
Prescription Painkiller Overdoses in the US
Prescription painkiller overdoses killed nearly 15,000 people in the US in 2008, more than triple the 4,000 in 1999, and now outnumber deaths from heroin and cocaine combined. About 12 million Americans reported nonmedical use of these drugs in 2010.
Drug
A Blockbuster Drug That Causes Cancer, TB and Lethal Infections
The writer argues Abbott built Humira into an $8 billion-a-year drug through an early FDA approval, PR firms, doctor outreach, free samples to seniors and heavy consumer advertising, even though TNF blockers are linked to tuberculosis, rare cancers and lethal infections.
Drug
Study finds that annual screening with chest x-ray does not reduce rate of lung cancer deaths (PR)
In the PLCO trial, 154,901 people aged 55 to 74 were randomly assigned to four years of annual chest radiographs or usual care. Those screened did not have a significantly lower rate of death from lung cancer, researchers report in JAMA.
Drug
The New Epidemic Sweeping Across America (and it's Not a Disease)
A Los Angeles Times analysis of 2009 CDC data found drugs killed more Americans than motor vehicle crashes for the first time, 37,485 against 36,284, driven by prescription painkillers and anxiety medications rather than street drugs. The death toll was highest among people in their 40s.
Drug
The Dark Truth About the "Wonder Drug" Millions Swear By
Dr. Stephanie Seneff argues that drug trials run too short to catch long-term harm, and that retrospective studies crediting statins really reflect the years of high cholesterol that preceded treatment. She calls cholesterol the wonder drug and lists 13 sites on statins for readers.
Drug
Antidepressant linked to developmental brain abnormalities in rodents (PR)
Rats given the SSRI citalopram during key stages of brain development showed brain abnormalities and behavior characteristic of autism spectrum disorders. Lead investigator Rick Lin cautions it would be premature to tell pregnant women to stop taking SSRIs.
Drug
Feed a cold -- starve a tumor(PR)
In mice, TSC2-negative tumors grew larger on a carbohydrate-free diet than on a western-style diet, but the glucose analogue 2-deoxyglucose, which disrupts glucose metabolism, shrank tumors on either diet, University of Washington researchers report in Cell and Bioscience.
Drug
High rate of false-positives with annual mammogram
A study of nearly 170,000 women aged 40 to 59 found that more than half of cancer-free women screened annually for a decade were recalled for false-positive results and about one in 12 sent for biopsy. Screening every other year cut that probability from 61 to 42 percent.
Drug
Zoledronic acid reduces the recurrence of breast cancer in post-menopausal women (pr)
The AZURE trial of 3,360 patients with stage II/III breast cancer found no overall benefit from adding zoledronic acid, except among women who had gone through menopause at least five years earlier: 85 percent overall survival versus 79 percent without the drug.
Drug
Virus kills breast cancer cells in laboratory (PR)
Penn State researchers report that adeno-associated virus type 2, which infects people without causing disease, killed human breast cancer cells in the laboratory across three cancer types representing multiple stages of the disease. They say it opens possible new therapies.
Drug
Study suggests possible link between two Type 2 diabetes drugs and pancreatic cancer
A UCLA review of FDA adverse event reports from 2004 to 2009 found a six-fold higher odds ratio for reported pancreatitis among people taking sitagliptin or exenatide than among users of four other diabetes therapies, plus more reported pancreatic cancer.
Drug
Was Perry Wrong to Push HPV Vaccine?
The author questions Rick Perry's push for Merck's Gardasil, noting the vaccine covers strains behind 70 percent of cervical cancers but not all, does not replace Pap smears, costs $359.25 for three doses, and that fewer than a third of eligible young women started it.
Drug
New Stroke Prevention Trial has immediate Implications for Clinical Paractice
In an NIH-funded trial in the New England Journal of Medicine, patients at high risk of a second stroke who received intensive medical treatment alone had fewer strokes and deaths than those who also got a brain stent. Enrollment was stopped early in April.
Drug
The Widely Prescribed Drug that's No Better than a Placebo
Researchers found antipsychotics widely prescribed for severe post-traumatic stress symptoms in veterans worked no better than placebo and carried serious side effects. The study tested Risperdal, and the results likely extend to Seroquel, Geodon and Abilify.
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