IQWiG's final report found no proof that people with type 2 diabetes who do not use insulin benefit from glucose self-monitoring. The few suitable trials were too short and reported too little to show whether blood or urine testing offers any advantage.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
Antidepressants useless for mild or moderate depression
Jay Fournier and colleagues reviewed six trials covering 718 patients and found antidepressant efficacy depended heavily on how severe depression was at the outset, with meaningful benefit concentrated in severe cases and little to show for mild or moderate symptoms.
Drug
Expert Explains the Flu Vaccine Deception and the Swine Flu Hoax
Mercola interviews Shiv Chopra, a former drug-company scientist and 20-year senior adviser at what is now Health Canada, who says no flu vaccine has ever worked and calls swine flu and avian flu made-up hoaxes.
Drug
Antidepressants raise risk of death and stroke in older women
In the Women's Health Initiative, which followed 160,000 postmenopausal women for up to 15 years, those taking tricyclic or SSRI antidepressants were 45 percent more likely to have a stroke, especially the bleeding kind, and in one analysis 32 percent more likely to die.
Drug
Before You Take That Antidepressant, Visit This Web Site
SSRIstories.com collects 3,500 crime-related news reports involving SSRI antidepressants, sortable by drug, date, location and type of violence, with each story's drug citation pulled out and boldfaced. A 2009 Journal of American Physicians and Surgeons article cited the site.
Drug
FDA to study safety of medications during pregnancy
FDA announced a collaboration with the HMO Research Network's CERT, Kaiser Permanente research centers and Vanderbilt University to study medication safety in pregnancy, drawing on records covering about 1 million births from 2001 to 2007 at 11 medical sites.
Drug
Detection of early stage ovarian cancer may be possible
Researchers compared blood from 34 women with ovarian cancer and 70 without, testing six candidate proteins. Three began rising slightly about three years before diagnosis, though Garnet Anderson notes the levels do not look clearly abnormal until the final year before diagnosis.
Drug
Older Mexican Americans at higher risk of diabetes
Type 2 diabetes rates among Mexican Americans aged 75 and older doubled since 1993, Diabetes Care reports. Obesity rose from 20 to 29 percent and high blood pressure from 37 to 57 percent, while kidney and vision complications held steady and diabetics faced greater disability risk.
Drug
New diabetes drug waiting for FDA approval
Biodel asked the FDA to approve VIAject, an insulin it says the blood absorbs faster than existing analogs. A trial of more than 884 patients in the US, Germany and India reported faster glucose reductions, lower hyperglycemia and hypoglycemia risk and less weight gain.
Drug
Acupuncture reduces hot flashes, sweats in breast cancer patients
In a trial of 50 breast cancer patients on hormone therapy, acupuncture matched venlafaxine at reducing hot flashes and night sweats, and its effect lasted longer. Patients also reported more energy and clearer thinking, and a quarter reported increased sex drive.
Drug
Tylenol Arthritis Pain Caplet 100 count: Recall of all lots
McNeil widened its recall to every lot of Tylenol Arthritis Pain Caplet 100-count bottles with the red EZ-OPEN cap after reports of a moldy, musty odor accompanied by nausea, stomach pain, vomiting and diarrhea. The odor traces to 2,4,6-tribromoanisole from treated wooden pallets.
Drug
Will You Be one of the 15,000 That Are Killed By CT Scans Next Year?
Measurements from more than 1,000 patients at four hospitals suggest CT scans deliver far more radiation than earlier estimates based on dummies, with one scan equal to up to 442 chest X-rays. Mercola cites projections of 29,000 new cancers and 14,500 deaths a year.
Drug
Cure found for high blood pressure
Media reports describe renal sympathetic-nerve ablation, in which a wire threaded into a vessel near the kidneys burns nerves that drive blood pressure up. Ardian's chief medical officer, whose company makes the equipment, says it restores normal pressure within hours without side effects.
Drug
FDA rejects Traceva for earlier use in lung cancer patients
An FDA panel rejected Tarceva as maintenance treatment for advanced lung cancer patients who have finished chemotherapy. In a study of 889 such patients, median progression-free survival was 12.3 weeks on Tarceva against 11.1 weeks on placebo.
Drug
FDA unable to rule out vytorin-cancer link
In the SEAS trial of 1,873 aortic stenosis patients, Vytorin did not lower overall cardiovascular risk, and more patients taking it were diagnosed with and died from cancer than on placebo. The FDA said in December 2009 that a causal link is unlikely but cannot be ruled out.
Drug
Teva, OncoGenex join forces to develop prostate cancer drug
Teva and OncoGenex announced a December 21 licensing deal to develop and commercialize OGX-011, a drug meant to counter cancer treatment resistance, with Teva also buying OncoGenex shares. OGX-011 has completed phase II trials in prostate, lung and breast cancer.
Drug
FDA review cannot rule out Vytorin cancer link
After reviewing the SEAS trial and interim data from the SHARP and IMPROVE-IT trials, FDA said it believes Vytorin and Zetia are unlikely to raise the risk of cancer or cancer death, but cannot definitively rule it out. It is not advising anyone to stop the drugs.
Drug
The Medicines Co recalls High blood pressure drug
The FDA alerted pharmacists and risk managers to The Medicines Company's recall of 11 lots of Cleviprex, a blood pressure drug, after sub-visible stainless steel particles around 2.5 microns were found in the injectable emulsion. No other lots are affected.
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