A cocaine vaccine meant to blunt the drug's euphoric effects worked in 38 percent of study participants, though the effect wore off after two months. Lead researcher Thomas Kosten says the concept works but depends on the antibody levels each person reaches.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
Who Invented the Flu Vaccine?
Desperate Spanish flu treatments ranged from bleeding to intravenous hydrogen peroxide and a mix of blister fluid, strychnine, caffeine and morphine. Transfusing blood from recovered patients seemed to help and amounted to a crude first form of influenza vaccination.
Drug
Clinical Testing of Pancreatic Cancer Drug Called to Abrupt Halt
SciClone Pharmaceuticals halted all testing of its pancreatic cancer drug RP101 during phase 2 on a safety review board's recommendation. The piece notes the disease has no screening test and lists risk factors including age, male sex, diabetes, obesity and activity level.
Drug
Electronic Medical Systems Not Flawless
At a Houston VA medical center, 92 of 1,196 abnormal test alerts emailed to doctors drew no timely follow-up, about 8%, including imaging showing cancerous growths or aneurysms. Alerts sent to more than one clinician were less likely to be acted on.
Drug
Tylenol recall 2009
McNeil Consumer Healthcare recalled lots of Children's and Infants' Tylenol oral suspension after the bacterium Burkholderia cepacia was found in a raw material. The company says no bacteria were found in finished product, and the FDA reported no associated illnesses.
Drug
New AIDS vaccine promising
In a Thai trial of 16,000 volunteers, 51 of 8,197 people given a prime-boost HIV vaccine regimen became infected against 74 of 8,198 on placebo, about 30 percent lower risk and a moderate but statistically significant difference. The vaccines target strains common in Thailand.
Drug
During Liquid Tamiflu Shortage, Pharmacists Relearn the Art of Compounding
With liquid Tamiflu short, Roche is advising pharmacists how to compound capsules for young children and others who cannot swallow pills. Each prescription takes about 20 minutes and cannot be prepared in advance, since pharmacies are not allowed to manufacture medications.
Drug
Flu Vaccine Exposed
Dr. Mercola presents a Thinktwice Global Vaccine Institute video on how flu vaccine is made and what it contains, and argues that death caused directly by the flu virus is rare. He attributes most so-called flu deaths to bacterial pneumonia, which antibiotics rather than a flu shot treat.
Drug
FDA MedWatch:Tamiflu (oseltamivir) for Oral Suspension: Potential Medication Errors
The FDA alerted prescribers and pharmacists that Tamiflu oral suspension is dosed in milligrams while liquid prescriptions are usually written in milliliters or teaspoons, and it has received reports of instructions that do not match the 30, 45 and 60 mg dispenser.
Drug
VERY Important Vaccine Question
Mercola relays the National Autism Association's question to the FDA: how much longer will it approve vaccines never tested in combination with one another? He notes the U.S. schedule calls for 48 doses of 14 vaccines by age 6 and says the full schedule has not been safety tested.
Drug
New Formulation of OxyContin May Reduce Abuse Potential
FDA scientists said Purdue Pharma's plastic-coated reformulation of OxyContin is not fully abuse-resistant but may be better than current versions, ahead of an advisory panel vote. Crushed or chewed, the drug delivers a heroin-like high.
Drug
Flu linked to deaths from heart attack and heart disease
A review of 39 studies from 1932 to 2008 found 30 to 50 percent more deaths from heart disease and heart attacks during flu season, and linked vaccination to lower risk of dying. The article argues vitamin D deficiency may explain the seasonal pattern.
Drug
Accidental Prescription Drug Deaths Spike Upward
U.S. deaths from unintentional injury rose 11 percent between 1999 and 2005, with poisonings among people aged 15 to 64 and falls among those 45 and older making up 89 percent of the increase. Researchers attribute much of the poisoning rise to prescription drugs.
Drug
Why you should not vaccinate your children against the flu this season
The piece relays Bill Sardi's article listing eighteen reasons he says parents should not give children the H1N1 flu vaccine, among them that the virus is less virulent than seasonal flu, that adjuvants and thimerosal carry risks, and that trials used mock vaccines in healthy volunteers.
Drug
New guidelines to cut needless radiation exposure
A UC Davis study of 42,000 children with head trauma at 25 hospitals found nearly a quarter of children under two, and one in five older children, received unneeded CT scans. Researchers offer prediction rules to spare low-risk children the radiation, not to replace clinical judgment.
Drug
Daily Aspirin Regimen May Not be Prudent for Healthy People
A Lancet review of 22 studies and 100,000 people found daily aspirin prevented 5 vascular events per 10,000 among those who had never had one, while causing 3 extra cases of gastric bleeding. For people with a prior event it prevented 150 events per 10,000.
Drug
Breast Cancer Drugs Not Without Their Own Risk
Women who learn they carry a breast cancer mutation face hard choices. Annals of Internal Medicine reports raloxifene and tamoxifen can cut invasive breast cancer risk by up to half - 7 to 10 fewer cases per 1,000 women - while adding 4 to 7 blood clots per 1,000.
Drug
H1N1 vaccines approved by the FDA
The FDA approved H1N1 vaccines and expects national distribution in a few weeks. Early adult trials showed a robust immune response 8 to 10 days after one dose; child doses are still being studied. Some formulations contain thimerosal; people with severe egg allergy should not be vaccinated.
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