Researchers at Kaohsiung Medical University in Taiwan tested roots of Ferula asafetida, used against the 1918 influenza pandemic, and found some of its compounds killed H1N1 virus as potently as a prescription antiviral. They say the finding may aid new drug development.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
Vivus Set to Apply for FDA Approval for Qnexa
Vivus plans to seek FDA approval for Qnexa, a combination of phentermine and Topamax. Across two late-stage trials of 1,267 and 2,487 patients, those on the drug lost about 9% of body weight, nearly double the 5% the FDA requires, and lowered blood lipids and blood sugar.
Drug
Why Mammography is NOT an Effective Breast Cancer Screen
Dr. Len Saputo reviews the limits of mammography, clinical breast exams, ultrasound, MRI and PET scans, then makes the case for breast thermography. Early infrared scanners produced misdiagnoses, but he says modern versions rest on research covering more than 300,000 women.
Drug
Another Shocking Warning About Swine Flu Vaccine
German lung specialist Wolfgang Wodarg warned that the H1N1 vaccine's nutrient solution uses cancerous animal cells, raising fears about injecting them. Mercola adds that a BMJ study found more than half of public hospital doctors and nurses would refuse the vaccine.
Drug
Fish-Killing Toxin Could Kill Cancer Cells
ARS and NOAA researchers report in Toxicon that euglenophycin, the algal toxin blamed for killing more than 21,000 striped bass at a North Carolina fish farm in 2002, resembles a fire ant venom alkaloid known to inhibit tumours and may have cancer-killing properties.
Drug
Why You Should Get Off Prescription Acid-Reducing Drugs ASAP
In a study of healthy volunteers who had never had heartburn, more than 40 percent developed heartburn, acid regurgitation or dyspepsia in the weeks after eight weeks of proton pump inhibitors were stopped, a rebound in acid secretion that can lead to dependence on the drugs.
Drug
New drug beats warfarin in reducing stroke risk
A study presented in Barcelona found the experimental anti-clotting drug dabigatran cut stroke risk in 18,000 patients with atrial fibrillation more than warfarin did. Patients on dabigatran were also slightly more likely to suffer a heart attack or stomach pain.
Drug
Study Reveals Limitations of Tamoxifen
In a Cancer Research study of 1,100 women with estrogen-sensitive tumors, five years of tamoxifen cut recurrence risk by 60 percent. Those same long-term users were four times more likely to develop a rare, aggressive breast cancer that is not estrogen sensitive, which tamoxifen cannot treat.
Drug
Weight loss drug Alli linked to liver injuries
The FDA is reviewing orlistat, sold as prescription Xenical and over-the-counter Alli, after 32 reports of serious liver injury between 1999 and 2008, including 27 hospitalizations and six liver failures. No definite link is established, and the agency says to keep taking it as directed.
Drug
ADHD drug-related abuse calls rise 140%
A Pediatrics study found calls to poison centers about teens abusing ADHD stimulants rose 76 percent from 1998 to 2005, and 140 percent per million adolescent prescriptions. Amphetamine prescriptions rose 133 percent over the same period, and case severity increased.
Drug
Government Report Supports Gardisil Efficacy
A government analysis of more than 12,000 young women vaccinated between June 2006 and December 2008 found Gardasil safe, estimating 59 adverse reactions per 100,000 vaccinated, most commonly fainting. Some doctors remain hesitant about routine vaccination at ages 11 and 12.
Drug
Nutracoastal Trading LLC expands recall of Steam dietary supplement
Nutracoastal Trading has widened its July 2009 recall of the supplement STEAM after finding a lot containing tadalafil, an erectile dysfunction drug ingredient. The company says the undeclared ingredient can dangerously lower blood pressure in people taking nitrates. No illnesses are known.
Drug
Half of kids given flu drug have side effects
Studies of 103 children found 51 to 53% had at least one side effect from Tamiflu: nausea in 29%, stomach pain or cramps in 20%, sleep problems in 12%, and neuropsychiatric effects such as nightmares in nearly one in five. A British Medical Association expert says the drug is overused in mild cases.
Drug
What you need to know about breast implants
After police identified a murdered woman by the serial number on her breast implants, the piece reprints FDA background on the saline-filled and silicone gel-filled implants approved for augmentation and reconstruction.
Drug
Antidepressant Therapy: Risky for Pregnant Women?
A joint report from the American Psychiatric Association and the American College of Obstetrics & Gynecology finds doctors still unsure whether SSRIs pose significant risk in pregnancy. Both urge women to weigh risks with their doctors, and flag patients who should not stop treatment.
Drug
Canadian Study Encouraging to Medical Heroin Backers
A Canadian trial in the New England Journal of Medicine divided 251 heroin addicts among methadone, medical heroin and the painkiller Dilaudid. Sixty-seven percent of those given heroin stayed in treatment, against 48 percent on methadone. Up to a quarter of addicts respond poorly to methadone.
Drug
Diabetes drug linked to increased risk of heart failure
A cohort study of 40,000 Canadian diabetes patients aged 66 and older found significantly lower rates of heart failure and death with pioglitazone than rosiglitazone, though heart attack rates were similar. The authors stop short of calling pioglitazone safer.
Drug
Warning: Swine Flu Shot Linked to Killer Nerve Disease
A leaked Health Protection Agency letter told UK neurologists to watch for a rise in Guillain-Barre Syndrome, a paralysing nerve disorder that could be triggered by the swine flu vaccine. It cites the 1976 US vaccine, withdrawn after ten weeks once a GBS link became clear.
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