In a six-month trial at Australia's Genomics Research Center, 52 diagnosed migraine sufferers took either folic acid with vitamins B6 and B12 or a placebo. Those on the vitamins cut homocysteine 39% while controls saw no change, and migraine disability fell from 60% to 30%.
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Nutrition
Vitamins, minerals, supplements, herbs and diet: the research on how what we eat shapes our health.
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Food
Caffeine before workouts may help moderate muscle pain
In a study of 25 college-aged men who cycled for 30 minutes, those given 5 mg of caffeine per kilogram of body weight reported a moderate reduction in quadriceps pain against placebo. The researcher says more work is needed beyond this group.
Vitamins
Vitamin D theory of autism
Dr. John Cannell of the Vitamin D Council sets out his theory that vitamin D deficiency during pregnancy or childhood causes autism, arguing it fits the rise in cases alongside sun avoidance and the patterns among twins, boys and black children. He calls it an unproven but disprovable theory.
Supplements
Grape seed extract the new cure for leukemia?
Researchers at the University of Kentucky and China's Third Military Medical University report that 76 percent of leukemia cells died within 24 hours of exposure to grape seed extract, with higher doses having greater effect. Lead author Xianglin Shi says it is too early to claim prevention.
Diet
High-fat diet helps control epileptic seizures
A tightly regimented ketogenic diet of whipping cream, butter and oil cut seizures by as much as 90 percent in half of 43 epileptic children at Children's Hospital of Wisconsin. Dr. Mary Zupanc warns it cannot be tried without close medical monitoring and precise supplementation.
Diet
Broccoli cuts stomach cancer risk
Fifty Japanese volunteers ate 2.5 ounces of broccoli or alfalfa sprouts daily for two months; the broccoli group's H. pylori colonization fell 40 percent while alfalfa showed no change. Levels rebounded after people stopped, and the bacteria were never fully eradicated.
Minerals
Iron: the new cancer killer?
German Research Center scientists report that flooding lymphoma cells with iron sets off free radicals and oxidative stress severe enough to kill them. With Mannheim University Hospitals they studied the approach in Sezary's disease and in lymphomas that resist other treatment.
Nutrition
Grape seed extract helps prevent obesity
Hamsters at the University of Montpellier fed a high-fat diet plus Chardonnay grape seed extract for 12 weeks did not gain the abdominal fat seen in high-fat controls, and were partly spared rises in blood sugar, triglycerides, insulin and insulin resistance.
Vitamins
CoQ10 prevents pre-eclampsia in pregnant women
In an Ecuadorian placebo-controlled trial, pregnant women took 200 mg of CoQ10 daily from 20 weeks' gestation; pre-eclampsia occurred in 14 percent of them against 25.6 percent on placebo. Researchers say more study is needed to explain how the antioxidant helps.
Food
Matzo ball soup may help lower high blood pressure
A study in the Journal of Agricultural and Food Chemistry identified four peptides from chicken leg collagen that can act as ACE inhibitors, which may lower blood pressure. The researchers note chicken breast muscle does not yield the same materials.
Diet
Maternal personality affects child's eating habits
In a Norwegian study of 27,763 mothers, those who were emotionally unstable, anxious, angry or low in self-confidence more often fed their 18-month-olds sweet and fatty foods. Daily smoking, high BMI and more children tracked the same way; older, better-educated mothers did not.
Supplements
Pea protein helps kidney health, lowers blood pressure
Rats with polycystic kidney disease given a small daily dose of yellow pea protein hydrolysate had blood pressure 20 percent lower after eight weeks and urinated up to 30 percent more, back to normal levels. A trial in mildly hypertensive people is under way.
Diet
The truth about vegetarianism in young adults
A study from three universities found 15- to 23-year-olds following vegetarian diets were more likely than others to binge and purge or misuse diet pills and diuretics, though they were less often obese. The writer urges parents and clinicians to ask why a teen switches diets.
Supplements
Fish oils offer no heart benefit
At the American College of Cardiology meeting, the OMEGA trial reported no difference between nearly 4,000 heart attack patients given omega-3 supplements and those given placebo, echoing a 2006 review of 89 trials and cohort studies that found no mortality or cardiovascular benefit.
Vitamins
Health Benefits, Consequences of Folic Acid Dependent on Circumstances
Two Nutrition Reviews articles by Omar Dary and Joel Mason weigh folic acid's benefits against its risks: folate protects against some cancers and neural tube defects, but because it drives DNA synthesis, abundant intake may also speed the growth of pre-cancerous and cancerous tumors.
Food
Soy food prevents breast cancer
A case-control study of 597 women with breast cancer and 966 without, across three Asian-American groups, tied the highest childhood soy intake to 60% lower risk. Adolescent and adult intake showed weaker links that faded after adjusting for westernization.
Food
Garlic could help patients with diabetes or high blood pressure
Kuwait University researchers treated diabetic and hypertensive rats with garlic for three weeks and found serum glucose and systolic blood pressure fell, while antioxidant levels including glutathione and vitamin C rose above baseline.
Vitamins
Vitamin B and folic acid may reduce AMD risk
In a trial of 5,205 women at high heart-disease risk, those randomly assigned folic acid plus vitamins B6 and B12 for an average of 7.3 years were 34 percent less likely to develop age-related macular degeneration and 41 percent less likely to develop visually significant AMD than those on placebo.
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