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Obesity

Weight, obesity and weight loss.

Obesity

Caffeine/green tea supplement, another weight loss aid

In a trial of 76 overweight and moderately obese adults who first lost about 5.9 kg on a very low energy diet, a green tea and caffeine mix helped habitual low caffeine consumers keep losing weight and fat over three months, but did nothing for high caffeine consumers.

Obesity

New weight loss weapon: Caffeine/ephedra dietary supplements

In a small trial, 40 overweight or obese people took a supplement with 70 mg herbal caffeine and 24 mg ephedra, or a placebo, three times daily. At 12 weeks the supplement group had lost 3.5 kg against 0.8 kg, and 7.9 percent of body fat against 1.9 percent.

Nov 15, 2012

Obesity

Can When You Eat Affect Your Health?

Salk Institute researchers fed mice a high-fat, high-calorie diet, giving one group food around the clock and another only eight hours a night. On equal calories, the time-restricted mice stayed lean and avoided high blood sugar and fatty liver; the all-day group became obese.

Nov 7, 2012

Obesity

Diet and Exercise Reverse Leptin Resistance, Thereby Promoting a Healthy Weigh

Mercola writes that leptin and insulin together govern metabolism and that resistance to both accompanies obesity. Research in Molecular Cell describes the leptin receptor's hinged legs locking onto leptin and signaling the enzyme Janus kinase, which researchers see as a drug target.

Oct 29, 2012

Disease

Obesity - one of risk factors for chronic myelogenous leukemia

Comparing 253 chronic myelogenous leukemia patients with 270 controls, Texas researchers found patients were three to five times more likely to have been obese at 25, at 40 and at diagnosis. Those gaining more than 1 kg a year from 25 to 40 were 263 percent more likely to be diagnosed.

Oct 28, 2012

Obesity

What Does It Mean to Be Fat Adapted?

Mark Sisson explains what he means by fat-adapted: a body that readily oxidizes stored fat for fuel, which he calls the normal human metabolic state. A sugar-burner, by contrast, cannot access body fat well and gets ravenously hungry hours after eating.

Aug 11, 2012

Obesity

Are Soft Drinks the Only Reason We're Fat?

Two thirds of U.S. adults are overweight and a third obese. The piece weighs the dispute over whether obesity always harms health, citing Lancet projections of extra U.K. heart disease, diabetes and cancer cases by 2030, higher dementia risk, and the job and cost figures from the OECD.

Jun 4, 2012

Disease

Obesity reduces sexual functioning

A review in Obesity of 47 studies found the evidence consistent that obesity goes with reduced sexual functioning: obese men more often reported erectile dysfunction, women reported more problems overall, and most weight-loss studies found improvement afterward.

Apr 28, 2012

Obesity

Something better than orlistat in preventing obesity or weight gain

Belgian researchers testing plant phenolics found epigallocatechin-3-gallate, kaempferol and quercetin inhibited pancreatic lipase, the fat-digesting enzyme, more strongly than the anti-obesity drug orlistat. EGCG, found in green tea, was the most potent.

Apr 26, 2012

Diet

Very low calorie diet helps obese people with type 2 diabetes

Fourteen severely obese people with type 2 diabetes spent a week on a very low calorie diet, and their glucose disposal rose from 59 to 75.5 ml/min/m2 alongside lower fasting glucose and triglycerides. The authors credit better beta cell function, not insulin sensitivity.

Mar 22, 2012

Drug

Obesity raises death risk tied to sleeping pills (PR)

Researchers told an American Heart Association meeting that obesity nearly doubled the death rate tied to sleeping pills, even among people prescribed 18 or fewer pills a year, about one extra death annually per 100 obese patients. Men on the pills were about twice as likely to die as women.

Mar 18, 2012

Diabetes

Calorie restriction helps severely obese diabetics

In a study from the University of Rome Tor Vergata, seven days of a 400-calorie diet lowered fasting glucose and triglycerides in severely obese type 2 diabetes patients and improved both phases of insulin secretion, with 3.22% weight loss and no gain in insulin sensitivity.

Mar 11, 2012

Obesity

This Trick May Force Your Body to Burn 400-500 Extra Calories/Day

Mercola describes a study in which cooling activated brown fat in adult men, who burned more calories and lost white fat, plus animal work suggesting exercise converts white fat to brown by way of irisin. He relays Tim Ferriss's ice-pack, ice-water and cold-shower suggestions.

Feb 13, 2012

Obesity

The Root Cause of Excess Flab Almost Everyone Ignores

The U.S. PIRG report Apples to Twinkies calculates that a year of farm subsidies buys each taxpayer 19 Twinkies but less than a quarter of an apple. Mercola argues subsidies prop up agribusiness while another arm of government funds anti-obesity campaigns.

Feb 4, 2012

Obesity

Would you stop eating out to lose weight? (PR)

Thirty-five perimenopausal women who eat out often took a six-week Mindful Restaurant Eating course aimed at preventing weight gain. Reported in the Journal of Nutrition Education and Behavior, the intervention group lost significantly more weight and ate fewer calories and less fat.

Jan 11, 2012

Obesity

When overeating, calories, not protein, contribute to increase in body fat

In a JAMA study, 25 healthy volunteers overate diets drawing 5, 15 or 25 percent of calories from protein under inpatient conditions. The low-protein group gained the least weight, but calories rather than protein appeared to drive the increase in body fat.

Jan 6, 2012

Disease

Obesity, diabetes boost death risk from colorectal cancer

Two Journal of Clinical Oncology studies found people who were overweight or had type 2 diabetes when diagnosed with colorectal cancer fared worse. In the first, of 2,303 patients, being overweight at the outset carried a 30 percent higher risk of death from any cause and 35 percent from the cancer.

Dec 31, 2011

Obesity

Taking dieting breaks helps weight loss

In a four-month study of 115 women, those who restricted calories just two days a week lost about 9 pounds against 5 pounds on a standard Mediterranean diet, and cut insulin and cancer-promoting hormones more. Researchers note the setting was tightly controlled and want more work.

Dec 20, 2011

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