Analyzing 1,197 cases and 2,015 controls, City of Hope researchers found women aged 45 to 64 who started oral contraceptives at 18 had 2.9 times the risk of triple-negative breast cancer. No link appeared for other subtypes, and long breastfeeding lowered risk.
Section archive
Page 11 of 12
Breast Cancer
- All desks
- Abortion
- Accutane
- Acetaminophen
- Acid Reflux
- Acidic Foods
- Acne
- Acrylamide
- Acupuncture
- Additives
- ADHD
- Adiposity
- Advisories
- Aerobic Exercise
- Aflatoxin
- Agave
- Agent Orange
- Aging
- Agriculture
- AIDS
- Air Pollution
- Airline Passengers
- Airport
- ALA
- Alcohol
- Alcoholic Beverage
- Alerts
- Allergy
- Alli
- Aloe Vera
- ALS
- Alternative Medicine
- Aluminum
- Alzheimer's
- Amalgam
- AMD
- Ampyra
- Amygdala
- Anal Cancer
- And
- Anemia
- Angiogenesis
- Animal Protein
- Animals
- Anorexia
- Anthocyanins
- Anthrax
- Anti-Angiogenesis
- Anti-Obesity
- Antibacterial
- Antibiotic
Drug
Drug News: FDA expands use of breast cancer drug Tykerb
The FDA approved GlaxoSmithKline's Tykerb in combination with Novartis's Femara for hormone-positive, HER2-positive advanced breast cancer in postmenopausal women, after a study showed patients taking both lived longer than those on Femara alone.
Diet
Diet Affects Breast Cancer Risk
Mexican researchers reviewed 27 studies from Latin America and the Caribbean, linking fruit, vegetables, fish, fiber and folate to lower breast cancer risk and calories, red and processed meat, dairy, saturated fat and sucrose to higher risk. They call the food-specific evidence inconclusive.
Food
Fruit and Vegetables: Do They Reduce Breast Cancer Risk or Not?
Chemical
Acrylamide may boost certain breast cancers
Among 62,573 Dutch women followed 13 years, acrylamide intake showed no link to overall or receptor-negative breast cancer. Among never-smokers, the highest intakes tracked with 31% to 47% higher risk of ER-positive, PR-positive and joint receptor-positive tumours. The authors call for confirmation.
Disease
Teresa Heinz undergoes surgery for breast cancer
Heinz, 71, had lumpectomies on both breasts at Massachusetts General in early October and starts radiotherapy in January 2010. She has not decided on chemotherapy, weighing her age and the side effects against doctors' claim it would lift her survival odds to 99 percent.
Drug
Breast cancer may be diagnosed without biopsies
In mice, PET scans using 64Cu-TP3805 detected all eight malignant tumours by targeting the VPAC1 biomarker, while standard 18F-FDG scans found four; two benign tumours went undetected. Mathew Thakur says the approach would still need to hold up in humans.
Drug
New drug shrinks breast cancer
At the San Antonio Breast Cancer Symposium, researchers reported the antibody drug T-DM1 shrank tumors by 30 percent or more in 40 percent of women with HER2-positive metastatic breast cancer resistant to standard therapy, with median time to progression of 7.3 months and no survival comparison.
Diet
Fish oil helps prevent breast cancer
In rats, a maternal diet high in omega-6 fat raised carcinogen-induced breast cancer risk in female offspring, and adding fish oil during pregnancy and lactation lowered it. Fish oil given at puberty or in adulthood did not reduce the risk.
Nutrition
Soy cuts risk of breast cancer death, recurrence
Vanderbilt researchers followed 5,042 Chinese breast cancer survivors and found women with the highest soy protein intake were 29% less likely to die and 32% less likely to relapse than those with the lowest intake over an average 3.9 years.
Lifestyle
Loneliness raises breast cancer risk
University of Chicago researchers kept rats in isolation and exposed them to stress: the animals produced more corticosterone and showed a 3.3-fold increase in breast cancer risk, with 135 percent more tumors and far larger ones. Author Martha McClintock wants targets for intervention identified.
Drug
Mammogram screening: What you need to know (2)
Drawing on a 2002 Chicago Tribune report, and warning it cites no references, the piece lists mammography's downsides: Danish reviews questioning the early 30 percent mortality benefit, overdiagnosis of tumours that never turn dangerous, and no way to tell indolent cancers from aggressive ones.
Healthcare
Mammogram screening: What you need to know
The U.S. Preventive Services Task Force now recommends mammograms every two years for women aged 50 to 74 rather than yearly from 40, and advises against teaching breast self-examination. A companion review found biennial screening delivers most of the benefit with half the false positives.
Drug
Immune-Based Therapy May Hold Key to Breast Cancer
Johns Hopkins oncologist Leisha Emens is testing a vaccine meant to re-train the immune system to recognize tumour cells, paired with standard breast cancer drugs. She cautions that cancer is a range of diseases, so a single cure is unlikely.
Disease
Breast cancer more likely to return to women with dense breasts
Reviewing records of 335 Toronto women treated for invasive breast cancer, researchers found 21% of those with highly dense breasts had a recurrence over 10 years, against 5% of those with the least dense. They say more research is needed first.
Cancer
Vitamin D prevents breast cancer - study
A meta-analysis of 33 studies found women with high vitamin D intake were 9 percent less likely to develop breast cancer, and those in the highest quantile of circulating 25(OH)D 45 percent less likely. The highest calcium intakes went with 19 percent lower risk.
Drug
Mammogram screening does not cut risk of breast cancer death
Laura Esserman of UCSF and colleagues argue in JAMA that mammography mainly finds early-stage and indolent tumors, which raises survival rates without lowering deaths from aggressive breast cancer. They call for new tools to tell dangerous tumors from harmless ones.
Vitamins
Once again study suggests high vitamin D cuts breast cancer risk
Rejnmark's Danish case-control study of 142 women with breast cancer and 420 without found those in the top tertile of serum 25-hydroxyvitamin D were 48% less likely to have the disease, with the same pattern in receptor-positive and receptor-negative tumors.
209 stories