A review of 11 case-control studies in Anticancer Research found women in the highest quartile of serum vitamin D were 39 percent less likely to be diagnosed with breast cancer than those in the lowest, and women at 47 ng/ml of 25-hydroxyvitamin D were 50 percent less likely.
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Breast Cancer
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Cancer
High dietary fiber intake may help prevent breast cancer
A meta-analysis of 10 cohort studies covering 712,000 people found the highest fiber eaters were 11 percent less likely to develop breast cancer, with each 10-gram increase tied to a 7 percent lower risk. The authors note this does not prove fiber caused the reduction.
Supplements
Pregnant women's diet linked to risk of breast cancer in their daughters
Two mouse trials presented at the Era of Hope conference found daughters of mothers fed omega-3-rich canola oil in pregnancy had gene expression profiles tied to lower breast cancer risk, and daughters of mothers given methionine, choline, folate and B12 grew fewer, slower tumors.
Drug
Breast cancer drug herceptin boosts heart disease risk
Of 45 women aged 70 to 92 taking herceptin, 12 developed heart problems, an Annals of Oncology study found: 33% of those with prior heart disease versus 9.1% without. The authors say early trials enrolled younger, healthier women and urge caution in patients with heart disease or diabetes.
Cancer
Research links diet during pregnancy to breast cancer risk reduction in female offspring (PR)
Research presented at the Era of Hope conference suggests an expectant mother who eats more omega-3 fatty acids, or methyl nutrients such as methionine, choline, folate and vitamin B12, may reduce her daughter's later breast cancer risk. Some findings go further and hypothesise prevention.
Cancer
Diet, breast density and breast cancer risk
Harvard researchers compared 1,042 postmenopausal women with breast cancer to 1,794 without and found those with 50% or more breast density had triple the risk of women below 10%. Denser breasts went with in situ, larger, estrogen-receptor-negative and higher-grade tumours.
Cancer
Red meat linked to elevated breast cancer risk
In a Vanderbilt study of 2,386 breast cancer cases and 1,703 controls, women eating the most well-done red meat were 50 percent more likely to be diagnosed than those eating the least. The link ran stronger among postmenopausal women.
Vitamins
Low serum vitamin D linked to higher death risk in breast cancer patients
Among 1,295 postmenopausal breast cancer patients followed 5.8 years, each 10 nmol/L drop in pre-chemotherapy serum vitamin D corresponded to 8% higher death risk and 14% higher distant recurrence risk. Samples taken after chemotherapy began showed no such link.
Cancer
Caloric restriction may help fight breast cancer
Vitamins
Vitamin D relieves pain induced by aromatase inhibitors in breast cancer patients
In a phase II trial of 60 breast cancer patients taking anastrozole, Washington University researchers gave high-dose vitamin D2 or placebo along with daily calcium, and found supplementation was associated with less joint and muscle pain.
Cancer
Drinking coffee may reduce risk of breast cancer
Postmenopausal women drinking five or more cups of coffee a day were 57 percent less likely to have ER-negative breast cancer than those drinking one or fewer, in a Swedish analysis of 2,818 cases and 3,111 controls. The study was not a trial and cannot show cause.
Vitamins
Vitamin D cuts breast cancer risk
Laura Anderson of Cancer Care Ontario and colleagues report that women who spent 21 or more hours a week outdoors as adolescents were 29 percent less likely to develop breast cancer than those spending six hours, with reductions of 26 to 50 percent for time outdoors at later ages.
Drug
Radiotherapy for breast cancer boosts cardiovascular death risk
Following 4,456 women who survived breast cancer at least five years, French researchers recorded 421 cardiovascular deaths and found radiotherapy patients 76 percent more likely to die of cardiac disease, 56 percent for left-sided treatment. All were irradiated before 1984.
Diet
Eating Mediterranean diet may cut breast cancer risk
Premenopausal women who followed a Mediterranean diet most closely were 35 percent less likely to be diagnosed with breast cancer over nine years, in a UK cohort of 33,731 women. No link appeared in postmenopausal women, nor for the WHO healthy diet index.
Food
Can coffee fight breast cancer ?
Swedish researchers compared nearly 6,000 postmenopausal women and found those drinking five or more cups of coffee a day had a 57 percent lower risk of estrogen-receptor-negative breast cancer than women who drank less than a cup daily.
Food
Dietary fiber cuts breast cancer risk
Comparing 438 Chinese women with breast cancer to 438 without, researchers tied the highest total fibre intake to 69% lower risk. Vegetable fibre corresponded to a 52% reduction, fruit fibre 46% and soy fibre 27%, while cereal fibre showed no association.
Diet
Vegan Diet Reduces Breast Cancer Risk
Among 308 women at high genetic risk of breast cancer, those with the highest IGF-I levels had 3.5 times the risk of those with the lowest, and BRCA1 or BRCA2 carriers with high IGF-I were seven times more likely to develop the disease. Larger studies would be needed to confirm it.
Lifestyle
Acupuncture helps hot flashes in prostate cancer patients
Among 14 men treated for prostate cancer, twice-weekly acupuncture lowered an average hot flash score from 28.3 to 10.3 after four weeks and to 7 after eight, according to a study in the International Journal of Radiation Oncology. A randomized trial is being designed.
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