Modelling the Women's Health Initiative dietary change as a public programme, researchers put its cost at $13,773 per quality-adjusted life year for 50-year-olds and $10,544 for women at high breast cancer risk, cost-effective for society and Medicare but not for private insurers.
Section archive
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Breast Cancer
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Drug
Avastin not safe to treat breast cancer says FDA
The FDA says Avastin should no longer treat breast cancer after four studies showed it neither extended survival nor slowed progression enough to outweigh harms such as severe hypertension, hemorrhage, perforations and heart failure. Its approvals for colon, kidney, brain and lung cancer stand.
Drug
Zoledronic acid helps breast cancer patients
In 1,803 premenopausal women with endocrine-responsive early breast cancer, adding zoledronic acid cut disease-free survival events by 36 percent and death risk by 40 percent at 48 months, researchers told the San Antonio Breast Cancer Symposium. Results held at 62 months.
Drug
Women at risk of breast cancer fare better with early mammography
An 18-year review presented at the San Antonio Breast Cancer Symposium found mammography caught 31 percent of stage 0 breast cancers against 2.5 percent found by hand, suggesting women in their 30s with known risk may gain from screening before the usual age of 40.
Supplements
Study explains why omega-3 fatty acids prevent breast cancer
Omega-3 ethyl esters suppressed NF-kB transcriptional activity in luminal A, luminal B and basal breast cancer cell lines but had no effect on HER2-overexpressing cells, suggesting omega-3s may act against only some subtypes. Ongoing clinical trials should settle the question.
Miscellaneous
Elizabeth Edwards faced at least 2 risk factors
Elizabeth Edwards died Tuesday at 61, seven years after an invasive breast cancer diagnosis at 55 and three years after it spread beyond the breast. The piece argues she faced at least two risk factors: a first birth at 30 and long estrogen exposure implied by a last birth at 50.
Vitamins
Sunshine, vitamin D supplements needed to prevent breast cancer
Among 67,721 French women followed a decade, dietary and supplemental vitamin D alone showed no link to breast cancer, but in the sunniest regions the highest intakes came with 32 percent lower risk. The authors suggest a threshold of exposure from both sun and diet is needed.
Supplements
Soy Supplements Effective for Menopausal Symptoms - study
A double-blind Brazilian trial of 60 postmenopausal women found a soy supplement with 90 mg of isoflavone and hormone therapy improved hot flashes and muscle pain similarly, by 49.8 and 45.6 percent at 16 weeks. The authors say soy may be an effective alternative.
Lifestyle
Early menarche linked to higher risk of breast cancer
A case-control study of 115 breast cancer patients and 230 matched controls in northern Tanzania found later menarche linked to 26 percent lower risk in premenopausal women, while a high BMI at age 20 was linked to 31 percent higher risk. Longer lactation also tracked lower risk.
Food
Soy foods help fight breast cancer - studies
Xiao Ou Shu's Shanghai study of 5,042 Chinese breast cancer patients found those eating the most soy protein or isoflavones were 29% less likely to die over an average 3.9 years, despite concern that soy's estrogenic compounds might interfere with tamoxifen.
Vitamins
Should Jane Fonda take vitamin D to prevent breast cancer recurrence?
After Jane Fonda disclosed that a non-invasive breast tumor had been removed, this piece points to a Journal of Clinical Oncology study of 512 women with early breast cancer in which vitamin D deficiency was linked to 94 percent higher recurrence and 73 percent higher risk of death.
Miscellaneous
Jane Fonda diagnosed with non-invasive breast cancer
Fonda told Entertainment Tonight that a routine checkup found a small breast tumor a few weeks earlier, that the disease was non-invasive, and that surgery removed it and she is now cancer free. At 72 she is promoting new fitness DVDs.
Food
Eating soybean may reduce risk of breast cancer
Women with the highest soy isoflavone intake were 30% less likely to have an invasive breast cancer, in a comparison of 683 breast cancer patients with 611 healthy women. The associations showed up only among premenopausal women, and the design cannot establish cause.
Cancer
Eating vegetables, seafood may cut breast cancer risk - study
Comparing 357 Korean women with breast cancer to 357 age-matched controls, researchers found those eating the most vegetables and seafood were 86 percent less likely to be diagnosed. A meat-and-starch pattern showed no association, and menopausal status did not change the result.
Nutrition
Alcohol boosts pancreatic cancer risk - study
A meta-analysis of 21 case-control and 11 cohort studies in the International Journal of Cancer found people drinking three or more drinks a day were 22 percent more likely to develop pancreatic cancer. Separately, British scientists rated alcohol the most harmful drug overall.
Disease
Breast density, lobular involution linked to breast cancer risk
Among 2,666 women with benign breast disease followed 13 years at the Mayo Clinic, 6.5 percent developed breast cancer. Breast density and extent of lobular involution acted as independent risk factors, and dense breasts with no involution carried the higher risk.
Food
Green tea helps prevent breast cancer or not?
A Japanese study of 53,793 women found no overall link between green tea and breast cancer over about 14 years. Those drinking 5 or more cups a day were 12 percent more likely to be diagnosed than those drinking under one a week, but the difference was not statistically significant.
Disease
True negatives not at high risk for invasive breast cancer
Researchers followed 375 US women who tested negative for the BRCA1 or BRCA2 mutations their close relatives carry. Over 4.9 years they saw two invasive breast cancers against four expected, and two in situ cases against 0.9 expected. The study is small and a health observer cautions about errors.
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