In the Nurses' Health Study, postmenopausal women whose activity equalled walking more than an hour a day were 15% less likely to develop breast cancer than those doing less; brisk walking was tied to a 10% reduction. Researchers counted 4,782 invasive cases over 20 years.
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Breast Cancer
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Cancer
Meat, dairy products, sugar may up breast cancer risk - studies
Two studies tie insulin-like growth factor I to breast cancer: French researchers measured higher average serum IGF-I in 44 patients than in 92 controls, 26 versus 20 ng/ml, and a second found top-quartile women 92 percent more likely to be diagnosed, an association seen only in Caucasian women.
Chemical
Carcinogen in fries linked to breast cancer in younger women
A UK Women's Cohort Study analysis in the British Journal of Cancer found dietary acrylamide, a carcinogen present in fries and chips, was not linked to breast cancer overall but, after adjustment, was associated with a 20 percent higher risk in premenopausal women. The authors call the link weak.
Vitamins
Too much folate may boost breast cancer risk - study
Among 70,656 postmenopausal women followed from 1992, 3,898 developed breast cancer, and those in the highest quintile of dietary folate intake had a 12% higher risk. The authors saw no dose-response trend, and found no link for vitamin B-6, B-12 or total folate.
Lifestyle
White smokers get breast cancer earlier than non-smokers - study
A case-control study of 6,000 breast cancer patients in The Breast Journal found white women with any smoking history were 20% more likely to be diagnosed at 55 or younger than never-smokers, and less likely to get breast-conserving treatment. No significant link appeared among black patients.
Food
Update: Drinking green tea helps prevent breast cancer
An added warning says bottled green tea often contains little EGCG, so readers who want the effect must brew their own leaves. The underlying Harvard review of nine studies found more than three cups a day correlated with 27 percent lower breast cancer recurrence risk.
Food
Tea, coffee don't cut breast cancer risk in black women - study
Boston University researchers tracking 52,062 women in the Black Women's Health Study recorded 1,268 breast cancers over 12 years and found no significant link to tea, coffee or caffeine. Four or more cups of tea a day tracked with 13 percent lower risk, but not significantly.
Vitamins
Antioxidants may help prevent breast cancer
An Indian study in the Asian Pacific Journal of Cancer Prevention measured plasma antioxidants in 225 women and found higher beta-carotene, vitamin E and vitamin C accompanying significantly lower breast cancer risk. Higher vitamin A levels went the other way, tracking with higher risk.
Drug
Unsafe at any dose: Hormone therapy boosts cancer death risk
A JAMA report finds hormone therapy raises the chance of dying from breast cancer, not only of developing it; the estrogen-plus-progestin combination was already tied to a 26 percent higher risk. An accompanying editorial questions even the lowest-dose, shortest-time advice.
Supplements
Choline, betaine may cut breast cancer death risk
Tracking 1,508 breast cancer patients on Long Island, researchers report in FASEB Journal that higher choline and betaine intake accompanied lower all-cause and breast cancer death in dose-dependent fashion. They call the nutrients a promising prevention strategy.
Food
Soy Foods help Prevent Breast Cancer Recurrence - Studies
Among 524 patients followed 5.1 years after breast cancer surgery, postmenopausal women with the highest soy isoflavone intake were 33 percent less likely to have a recurrence than those with the lowest. Death rates did not differ significantly between the groups.
Drug
Hormone therapy boosts breast cancer death risk - new study
Re-analysis of Women's Health Initiative data on 16,608 postmenopausal women found those assigned estrogen plus progestin for about 5.6 years were 25 percent more likely to develop invasive breast cancer over 11 years of follow-up, and more likely to die of the disease.
Food
Vegetables help cut risk of breast cancer - study
Following 52,000 women in the Black Women's Health Study for 12 years, researchers found no overall link between fruit and vegetable intake and breast cancer, but women eating two or more vegetable servings a day had 43 percent lower risk of ER-negative, PR-negative tumors.
Drug
Hormone therapy boosts risk of breast cancer death
In the Women's Health Initiative, 16,608 postmenopausal women took estrogen plus progestin or placebo for about 5.6 years and were tracked 11 years. Those on hormone therapy were 25 percent more likely to develop invasive breast cancer, and were more likely to die of the disease.
Cancer
HRT Linked to Breast Cancer Death Risk
A study reported in the Journal of the American Medical Association found women assigned to hormone replacement therapy were twice as likely to die of breast cancer as those on placebo, contradicting the belief that HRT-linked tumors are easier to treat.
Cancer
How Does Induced Abortion Raise Breast Cancer Risk?
Surgeon Angela Lanfranchi contributes a piece arguing that growing evidence ties induced abortion, though not miscarriage, to higher breast cancer risk. She stresses it is one factor among many: most women with breast cancer never had an abortion, and most who have had one never get it.
Chemical
Fries, chips linked to breast cancer - new study
Among 62,573 Dutch women followed 13 years, the highest acrylamide intakes showed no link to overall breast cancer risk. Receptor-positive cases rose among never-smokers, but not significantly. The study is observational and cannot show that acrylamide-rich foods raise risk.
Drug
Anti-osteoporosis drugs bisphosphonates may help reduce breast cancer risk?
A Journal of Clinical Oncology study of 4,039 postmenopausal Israeli women found those on bisphosphonates for more than a year had 28 percent lower breast cancer risk after adjustment. It was not a trial, so something else linked to the drugs could explain the difference.
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