Among 512 women with early breast cancer followed an average of 11.6 years, those deficient in vitamin D were 94 percent more likely to see a distant recurrence and 73 percent more likely to die than women with sufficient levels; after adjustment the gaps narrowed to 71 and 60 percent but held.
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Lifestyle
Physical Activity Cuts Breast Cancer (Death) Risk - New Studies
Christine Friedenreich's review of 73 studies found the most physically active women were at least 25 percent less likely to be diagnosed with breast cancer than the least active, with most studies showing a dose-response and recreational and household activity most protective.
Disease
Here is why having a baby reduces breast cancer risk
Drawing on material from the Breast Cancer Prevention Institute, the piece argues that an early full-term pregnancy converts cancer-prone type 1 and 2 breast lobules into cancer-resistant type 3 and 4, and that more menstrual cycles mean higher risk.
Lifestyle
Who says breast cancer patients should avoid pregnancy?
A meta-analysis of 14 studies covering 1,244 cases and 18,145 controls found women who became pregnant after a breast cancer diagnosis were 41 percent less likely to die of the disease, leading the authors to conclude pregnancy does not compromise survival.
Vitamins
Could Coenzyme Q10 boost breast cancer risk?
In a case-control study of 160 postmenopausal women with breast cancer and 289 matched controls, those with the highest plasma coenzyme Q10 were more than twice as likely to be diagnosed. The authors caution that high levels may reflect supplement use rather than cause the risk.
Disease
Pink news: Antibiotic use linked to breast cancer
A meta-analysis in Pharmacoepidemiology and Drug Safety pooled five case-control studies covering 13,069 cases and 73,920 controls and found women who had ever taken antibiotics were 17.5 percent more likely to be diagnosed with breast cancer, with a borderline dose-response effect.
Diet
Mediterranean diet linked to lower risk of breast cancer
Among 14,807 Greek women followed nearly nine years, diets scoring 2 points closer to the traditional Mediterranean pattern carried 12 percent lower breast cancer risk overall, which the researchers called not significant, and 22 percent lower risk after menopause. Younger women saw no benefit.
Lifestyle
Physical Activity cuts breast cancer risk even in BRCA mutation carriers
Among 725 BRCA1/2 mutation carriers, self-reported lifetime sports activity was tied to a 16 percent lower breast cancer risk, a reduction the authors called statistically insignificant; those averaging 11 to 22.7 MET hours a week had a 41 percent lower risk.
Disease
Pink News: Reproductive factors linked to breast cancer
An Iranian case-control study of 100 patients and 200 controls found later first pregnancy and abortion accompanying 310 and 193 percent higher breast cancer risk, while five or more births went with 91 percent lower risk. A Sri Lankan study tied longer breastfeeding to lower risk.
Nutrition
Having a child early cuts breast cancer risk
In the European Journal of Gynecology and Oncology, women who gave birth first at 25 or younger and had three or more pregnancies had 50 percent lower breast cancer risk than women who never gave birth. A Cyprus study found 46 percent lower risk with menarche after age 15.
Phytochemicals
Lignan Reduces Risk of Breast Cancer Death
Among 112 women with breast cancer, postmenopausal patients in the highest quartile of dietary lignan intake were 71% less likely to die of breast cancer and 51% less likely to die of any cause than those in the lowest quartile. High dried bean intake tracked with 39% lower breast cancer death risk.
Supplements
Omega-3 fatty acids help prevent breast cancer - study
Among 72,571 cancer-free women in the Shanghai Women's Health Study followed about eight years, those eating little marine omega-3 fat alongside a lot of omega-6 fat were twice as likely to develop breast cancer as women with high marine omega-3 intake.
Vitamins
Vitamin D helps prevent breast cancer
A German Cancer Research Center meta-analysis of ten studies found each 20 ng/mL rise in serum vitamin D accompanying 41 percent lower breast cancer risk in case-control studies and 8 percent in nested case-control studies. A Shanghai team's meta-analysis reached a similar conclusion.
Food
Drinking Green Tea Good for Breast Cancer Survivors
In a six-month trial, 54 overweight breast cancer survivors who drank decaffeinated green tea cut their energy intake, lost a little weight and raised HDL cholesterol, but saw no significant change in the HDL/LDL ratio or insulin resistance.
Food
Pink News: Pomegranate juice may help prevent breast cancer metastasis
A laboratory study in Integrative Cancer Therapies found pomegranate fruit extract inhibited NF-kB-dependent gene expression linked to proliferation, invasion and motility in aggressive breast cancer cell lines, while lowering RhoC and RhoA protein levels.
Cancer
Pink Alert: Does Gasoline Increase Breast Cancer Risk in Men?
In the largest study of men diagnosed with breast cancer, Danish researchers found significantly higher rates among men who spent 10 years or more in jobs exposed to gasoline fumes and combustion, with the strongest effect in those who started before 40. Benzene is implicated.
Cancer
Pink Not Just for Women, Men Die From Breast Cancer, too
The American Cancer Society estimates 1,970 men will be diagnosed with invasive breast cancer and about 390 will die of it, a lifetime risk of roughly 1 in 1,000. Recent studies suggest men and women diagnosed at the same stage have equal survival prospects.
Cancer
Pink news: Plastic chemical may promote breast cancer development
A study in Environmental Health Perspectives found low nanomolar concentrations of bisphenol A blunted the effect of the chemotherapy drugs doxorubicin, cisplatin and vinblastine in two breast cancer cell lines, independent of the classical estrogen receptors. The work was done in cultured cells.
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