A study of Syrian women found breast tissue carrying both Epstein-Barr virus and high-risk HPV was associated with high-grade invasive ductal carcinoma and lymph node involvement, while either virus alone tracked with lower-grade tumors. Earlier work found EBV in 52% of 108 samples.
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Health News
Drugs, disease, healthcare, government and lifestyle: health news beyond the plate.
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Drug
Even A Small Meal Can Influence A Doctor's Prescribing Behavior
A JAMA Internal Medicine study indicates that even a small meal paid for by a drug company may sway what a doctor prescribes. The piece adds that researchers, politicians and journalists can be influenced by money too, and points to NPR's coverage and a database of payments to doctors.
Lifestyle
Recharge With Sleep: Pediatric Sleep Recommendations Promoting Optimal Health (PR)
The American Academy of Sleep Medicine issued its first consensus sleep recommendations for children: 12 to 16 hours a day for infants 4 to 12 months, tapering to 8 to 10 hours for teenagers 13 to 18, with naps counted for children under 6.
Drug
Tamoxifen - Known to be a human carcinogen
The 13th Report on Carcinogens lists tamoxifen as known to be a human carcinogen, citing evidence of a causal link to endometrial cancer. It also notes conclusive evidence that tamoxifen lowers the risk of cancer in the opposite breast and may prevent breast cancer in high-risk women.
Disease
Epstein-Barr virus, HPV linked to invasive breast cancer
Of 108 breast cancer samples from Syrian patients, 32% carried both Epstein-Barr virus and high-risk HPV, and that combination was associated with high-grade invasive tumors. Samples carrying only one virus were usually lower-grade ductal carcinomas.
Drug
Melatonin helps radiation-induced dermatitis in breast cancer patients
In a trial of 47 women having radiotherapy after breast-conserving surgery, grade 1 or 2 dermatitis appeared in 59 percent of those using melatonin cream against 90 percent on placebo, the Israel Medical Association Journal reports.
Lifestyle
Could antiperspirants increase breast cancer risk?
Writing in Morphologie, P.D. Darbre argues aluminum salts in antiperspirants may be a breast cancer risk factor, noting that tumors and cysts cluster in the upper outer breast nearest the underarm and that aluminum behaves like estrogen in laboratory studies.
Environment
Cancer is man-made
A University of Manchester study in Nature Reviews Cancer reports that only one of hundreds of Egyptian mummies showed cancer and ancient writings rarely mention it, which the authors read as evidence that cancer is largely man-made rather than genetic.
Environment
Which cell phone is safer: GSM-based or CDMA-based?
A study report suggests GSM phones, used on AT&T and T-Mobile networks, affect brain activity much more than the CDMA phones used by Verizon, Sprint and U.S. Cellular, raising the question of whether buyers should weigh network type when choosing a handset.
Environment
Breaking News: U.S. study links cell phone radiation to brain cancer
In a US government animal study, rats exposed to GSM or CDMA cell phone radiation from before birth developed glioma in up to 3.3% of exposed males and heart schwannomas in up to 6.6%, while no control rats developed either. Female rats appeared less susceptible.
Disease
FDA: Allergy Relief for Your Child
Weeks of sneezing with a stuffy or runny nose may point to allergic rhinitis rather than a cold, the FDA says. Up to 40 percent of children have it, and the agency, which regulates allergy medicines and allergen extracts, urges care when giving them to children.
Drug
Paternal x-ray exposure raises childhood leukemia risk
A 2010 case-control study found babies whose fathers had an abdominal x-ray before conception were 17 percent more likely to develop leukemia, 47 percent more likely after more than one x-ray, and over 256 percent more likely if the father had an intravenous pyelogram.
Disease
Potential risk factors for primary brain tumors
A Canadian review links adult primary brain tumors to genetic variants, pesticide exposure, farming or hairdressing work, processed meat and hair dye, and childhood cases to high birth weight and pesticide exposure. A separate meta-analysis tied vitamin C intake to lower glioma risk.
Drug
Dental CT scan linked to cancer risk
A retrospective cohort study of 505 patients by Taiwanese researchers links dental CT scans to some cancer risk, with mandible scans delivering higher x-ray doses than maxilla scans. Estimated lifetime risk ran from 1 in 16,196 for a 30-year-old woman to 1 in 114,680 for a 70-year-old man.
Drug
Radiotherapy for breast cancer increases death risk from heart disease
An Oxford-led meta-analysis of 75 breast cancer radiotherapy trials found women treated with radiotherapy were 30 percent more likely to die of heart disease and 23 percent more likely to develop a second cancer than those who were not. Higher radiation doses tracked with higher heart mortality.
Environment
Action Alert: "NO CONSENT" to Release of GM Mosquitoes
An Institute for Responsible Technology newsletter urging readers to comment to the FDA against releasing genetically modified mosquitoes before the April 12 deadline, and noting that Randal J. Kirk owns Oxitec, the GM apple company, and a majority stake in AquaBounty.
Healthcare
New UV-based Infection Prevention Device Fills Dangerous Gaps Between Robots, Germicidal Wipes and Bleaches
Advanced Ultra-Violet Systems has released the KR615 UV germicidal enclosure, which the company says kills 99.9 percent of C. diff and MRSA in 45 seconds. It sits bedside to decontaminate stethoscopes, cuffs, phones and other high-touch items that UV robots and wipes miss.
Drug
FDA enhances warnings for certain painkillers
The FDA is requiring a new boxed warning on immediate-release opioid painkillers covering misuse, abuse, addiction, overdose and death, plus added safety labeling across all prescription opioids. The agency calls it part of a broader plan to address the overdose epidemic.
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