A FASEB Journal report describes GCB-70, a green coffee bean extract from Cepham Inc. containing 70% chlorogenic acids, and argues it may aid weight management by boosting glucose and fat metabolism. Japanese studies suggest such extract inhibits pancreatic lipase.
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Supplements
Dietary supplements: evidence, safety and new products.
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Supplements
Sliming Diet Contains Hidden Drug Ingredient
The FDA warned consumers not to buy or use Sliming Diet after laboratory analysis found it contains sibutramine, a controlled substance pulled from the market in 2010 that can raise blood pressure and pulse and interact dangerously with other medicines.
Supplements
Toxin Discharged Tea Contains Hidden Drug Ingredient
FDA laboratory analysis found the weight-loss product contains fluoxetine, an SSRI. The agency warns consumers not to buy or use it, noting SSRIs carry risks of suicidal thinking, abnormal bleeding and seizures, and can trigger ventricular arrhythmia or sudden death with some medications.
Supplements
Sport Burner Contains Hidden Drug Ingredient
FDA analysis found that Sport Burner, a weight loss product sold online and possibly in stores, contains fluoxetine, an SSRI whose use has been tied to suicidal thinking, abnormal bleeding and seizures. The agency advises consumers not to buy or use it.
Supplements
Miraculous Evil Root Contains Hidden Drug Ingredient
FDA laboratory analysis found that Miraculous Evil Root, sold online and possibly in stores for sexual enhancement, contains sildenafil, the active ingredient in Viagra. The agency warns the undeclared drug can interact with nitrates and dangerously lower blood pressure.
Supplements
Gold Vigra Contains Hidden Drug Ingredient
FDA laboratory analysis found the sexual-enhancement product Gold Vigra contains undeclared sildenafil, the active ingredient in Viagra, which can interact with nitrates and lower blood pressure dangerously. The agency tells consumers to stop using it and throw it away.
Supplements
N-acetylcysteine supplements help pulmonary hypertension
Rats given monocrotaline to induce pulmonary hypertension and then treated with N-acetylcysteine showed less pulmonary vascular remodeling and lung inflammation, better total pulmonary resistance and improved right ventricular function, a Respiratory Research study reports.
Supplements
Study explains why green coffee bean extract helps weight loss
Japanese researchers found green coffee bean extract inhibited porcine pancreas lipase, with six chlorogenic acids accounting for more than 90% of the activity. Because lipase is needed to absorb fat, they suggest the extract could help prevent or treat obesity.
Supplements
Caffeine/ephedrine induces huge weight loss
In a 24-week trial of 90 obese adults published in Obesity, caffeine plus ephedrine, with or without leptin A-200, produced about 6% weight loss and cut whole-body fat mass, while leptin alone did not. The authors call the combination a modestly effective weight loss agent.
Supplements
DHA but not ALA lowers blood pressure
Mice on a high-fat diet given DHA for 12 weeks had systolic pressure 40 mmHg and diastolic pressure 15 mmHg lower than controls, while plant-derived ALA changed neither. DHA also cut several inflammatory cytokines and left less atheroma in the distal vessels.
Supplements
Kibow Biotech -- A "Buzz of BIO" Award Winner Presenting Investment/Business Opportunity on Emerging Field of "Gut Microbiome" with Probiotics and Prebiotics
Kibow Biotech of Newtown Square, Pa. won a 2014 BIO International Convention Buzz of BIO award, the first dietary supplement company to do so. Co-founder Natarajan Ranganathan says research on balancing the gut microbiome with probiotics is finally gaining recognition.
Supplements
Spirulina platensis may prevent pancreatic cancer
Spirulina platensis and its tetrapyrroles phycocyanobilin and chlorophyllin cut proliferation of human pancreatic cancer cells in a dose-dependent way and slowed tumor growth in xenotransplanted nude mice, according to a study in Annals of Hepatology.
Supplements
Spirulina maxima prevents liver damage induced by drugs
In rats, co-administering Spirulina maxima with the antituberculosis drugs isoniazid and rifampicin prevented the liver damage the drugs caused alone, and two weeks of the supplement restored already-damaged liver function, a study in a complementary medicine journal reports.
Supplements
Probiotics help improve quality of life in cystic fibrosis
In a randomized trial of 37 children aged 2 to 12 with cystic fibrosis, a month of daily probiotics improved mean quality-of-life scores at three months, though not at six, and significantly cut pulmonary exacerbations. The authors suggest the benefit fades without continued use.
Supplements
Chlorella supplements prevent heart disease
In a double-blind trial, 63 mildly hypercholesterolemic adults took 5 grams of chlorella or placebo daily for four weeks. The chlorella group cut total cholesterol 1.6% and triglycerides 10.3%, and raised lutein/zeaxanthin 89.6%. The authors tie the effect to carotenoid intake.
Supplements
Spinach supplements prevent exercise-induced oxidative stress
Twenty well-trained young men took spinach supplements or placebo daily for 14 days before running a half-marathon. Those on spinach held markers of oxidative stress and muscle damage lower afterward and raised total antioxidant capacity, the small study reports.
Supplements
Chinese herbal medicine fights breast cancer
A Journal of Ethnopharmacology study found the Chinese herbal decoction Shu-Gan-Liang-Xue inhibits aromatase and steroid sulfatase, two estrogen synthesis enzymes, in ER-positive breast cancer cell lines and in mice with ovaries removed, suggesting a possible adjunct therapy.
Supplements
Public Notification: La Jiao Shou Shen Contains Hidden Drug Ingredient
FDA laboratory analysis found the weight-loss product contains sibutramine, pulled from the market in 2010, and phenolphthalein, which studies indicate carries a cancer risk. The agency advises consumers not to buy or use it.
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