In mice with Ehrlich solid tumors, carotenoid-rich pequi oil protected the heart from doxorubicin damage better than vitamin C or E, which were ineffective and may raise the drug's kidney toxicity. Pequi oil also curbed tumor growth and boosted lymphocyte-dependent immunity.
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Supplements
Dietary supplements: evidence, safety and new products.
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Supplements
What to eat to keep the skin healthy?
A report in Postepy Dermatol Alergol suggests vitamin E, vitamin A, B vitamins, micro- and macronutrients and fatty acids may also protect the skin, adding to earlier findings on green tea and vitamin C against UVB damage.
Supplements
Testosterone new weapon to fight obesity ***
A. M. Traish's review reports that long-term testosterone therapy in men with testosterone deficiency brings sustained weight loss, smaller waists, lower BMI and better body composition, which he attributes to improved mitochondrial function, more energy use and greater physical activity.
Supplements
Fucoxanthin prevents cervical cancer?
Chinese researchers report that fucoxanthin triggered apoptosis in HeLa cervical cancer cells through the PI3K/Akt pathway and lowered NF-kB activation. They suggest it may suppress tumor growth in vivo and could become an anti-cervical cancer drug.
Supplements
Natural supplements for type 2 diabetes mellitus
A review names alpha-lipoic acid and fenugreek as the natural remedies most likely to lower blood sugar, followed by ivy gourd, gymnema and vitamin E. The authors warn that vitamin E can be toxic at high doses.
Supplements
Ginseng reduces oxidative damage induced by cell phone radiation
Rats exposed to simulated 900 MHz cell phone radiation four hours a day for 12 days suffered oxidative liver injury. Two ginseng preparations protected against it, raising superoxide dismutase and glutathione while lowering malonic dialdehyde and Nrf2 protein expression.
Supplements
Alpha-lipoic acid supplements fight chronic diseases
A review in Diabetology and Metabolic Syndrome reports that experimental studies have tested alpha-lipoic acid, a potent antioxidant, as a possible therapy for oxidative stress-related conditions including Alzheimer's disease, obesity, hypertension and diabetes complications.
Supplements
Citrus fruit compound may prevent obesity, reverse type 2 diabetes
Mice on a 40 percent fat diet given 5 mg per kg of sudachitin, a flavonoid from sudachi citrus peel, for 12 weeks showed improved glucose tolerance, insulin resistance and blood lipids, plus greater energy expenditure and mitochondrial biogenesis in skeletal muscle.
Supplements
Souvenaid(®) an effective medical food for Alzheimer's disease
A Journal of Alzheimer's Disease report details how each ingredient in Souvenaid, a Nutricia-developed nutrient mix of EPA, DHA, phospholipids, choline, uridine monophosphate, vitamin E and selenium, may protect against early-stage Alzheimer's. Trials are still running in several countries.
Supplements
Oxidative stress boosts hip fracture risk, antioxidants lower the risk
A Journal of Bone and Mineral Research study found women in the top 30 percent for a blood marker of oxidation products had 2.67 times the hip fracture risk of those in the bottom 30 percent. The piece suggests antioxidant supplements may reduce that risk.
Supplements
Gamma oryzanol supplements improve muscle strength
In a nine-week trial, 16 healthy men took 600 mg of gamma oryzanol daily and 14 took placebo alongside resistance training. The supplement group ended with different bench press and leg curl one-rep maximums, indicating greater strength, though body measurements did not change.
Supplements
Yerba Mate may help weight loss
Rats on a high-fat diet given 1 g/kg of aqueous Yerba Mate extract daily for four weeks gained less weight and had lower total cholesterol than rats not given the supplement, leading the authors to call it helpful against diet-induced metabolic dysfunction.
Supplements
Chlorella vulgaris supplements help NAFLD
In an eight-week trial at Tabriz University, 60 NAFLD patients took vitamin E with either chlorella vulgaris tablets or placebo. Both groups improved, but the chlorella group saw larger drops in weight, alkaline phosphatase and fasting blood sugar. Authors call it a possible add-on.
Supplements
Black seed, garlic help fructose induced metabolic syndrome
In rats fed a high-fructose diet, supplements of black seed or garlic, alone or together, largely restored the weight, cholesterol, triglyceride and liver enzyme changes the diet caused, King Saud University researchers report in the Journal of Oleo Science.
Supplements
Caffeine intake associated with lower incidence of tinnitus
Following more than 65,000 women in the Nurses' Health Study II for 18 years, researchers counted 5,289 cases of tinnitus and reported 15% lower incidence among women consuming 450 to 599 mg of caffeine a day than among those taking in under 150 mg.
Supplements
L-carnitine supplements help coronary artery disease
In a trial of 47 coronary artery disease patients, half took 1,000 mg of L-carnitine daily for 12 weeks. The supplement lowered malondialdehyde and raised antioxidant enzyme activity, which the authors read as reduced oxidative stress. Published in Nutrition Journal.
Supplements
Curcumin helps glyburide better treat type 2 diabetes mellitus
An open-label randomized trial of eight type 2 diabetes patients on glyburide found that 10 days of curcumin capsules lowered LDL, VLDL and triglycerides, raised HDL and improved glycemic control, researchers at Kakatiya University in India report.
Supplements
African herbal supplement may be used to treat Alzheimer's disease
Salk Institute scientists found extracts of the African plant Voacanga africana protected cells from oxidative stress, curbed inflammation and blocked beta-amyloid build-up, with the compound voacamine largely responsible. No animal or human trials have been run yet.
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