Baylor researchers fed a high-fat diet to mice bred as a model of Alzheimer's disease and saw calorie intake climb from 12 weeks, amyloid beta-peptide levels rise alongside it, and the animals turn obese and insulin resistant by 16 weeks.
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Vitamin D
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Comments
Vitamin D Council's future at risk — please help
An editor's note and appeal: the Vitamin D Council, the nonprofit founded by Dr. John Cannell, says donations have fallen sharply enough to put its existence at risk. Foodconsumer.org, which is not affiliated with the group, reprints Cannell's message and asks readers to donate.
Vitamins
Does Depression Cause Alzheimer's Disease? Vitamin D Helps Both!
A Neurology study of 949 Framingham participants found 22 percent of those depressed at the start developed dementia over 17 years, against about 17 percent of the rest. Author Jane Saczynski says the data cannot show whether depression causes dementia or the reverse.
Vitamins
High Doses of vitamin D result in lower blood pressure
In a small trial, type 2 diabetes patients given a single 100,000 or 200,000 IU dose of vitamin D3 showed moderately lower systolic blood pressure at eight weeks than those on placebo. Endothelial function, insulin resistance and HbA1c did not differ between groups.
Vitamins
Vitamin D fights HIV
Among 884 HIV-infected pregnant women in Tanzania followed about 69 months, those with serum vitamin D under 32 ng/mL were 25 percent more likely to progress to WHO stage III or worse and 47 percent more likely to develop severe anemia, a PLoS One study found.
Vitamins
Vitamin D boosts cognitive function
Tufts researchers analysed data on more than 1,000 home-care patients aged 65 to 99 and found those with sufficient vitamin D scored better on cognitive tests, particularly measures of executive performance such as reasoning and cognitive flexibility. Many participants were deficient.
Vitamins
New evidence: vitamin D prevents flu
A PLoS ONE study followed 198 healthy adults through autumn and winter: 16.6% of those who kept serum vitamin D at 38 ng/ml or higher caught a viral respiratory infection, against 45% of those with lower levels.
Sci-Tech
Model Predicts Individual's Vitamin D Needs
ARS physiologist Charles Stephensen and colleagues built a preliminary model predicting an individual's vitamin D needs, working with 72 young adults who logged what they ate and wore photosensitive badges for seven to eight weeks to measure sun exposure.
Nutrition
Breastfeeding and Vitamin D Overdose
The FDA warns that infants should not exceed the recommended 400 IU of vitamin D a day and tells caregivers to use only the dropper packaged with the product. Overdose can cause nausea, vomiting, appetite loss, excessive thirst, constipation and muscle weakness.
Cancer
Breast cancer survivors should take vitamin D - report
Mayo Clinic authors writing in Nutrition recommend breast cancer survivors keep adequate vitamin D stores for life, citing evidence that intake runs inversely to breast cancer risk, that higher levels track with better survival, and that up to 75 percent of patients are insufficient.
Letter to Editor
Vitamin D boosts physical performance
The Vitamin D Council's John Cannell writes that Chicago Blackhawks team physicians began diagnosing and treating vitamin D deficiency in all players about 18 months ago, most on 5,000 IU a day. His sources credit better performance plus fewer and milder colds and repetitive-use injuries.
Vitamins
Vitamin D newsletter: Vitamin D questions and answers
A Q&A from Dr. Cannell's vitamin D newsletter, covering how a reader in Germany can get adequate doses given customs limits on importing higher-dose supplements, and how to convert 25(OH)D results reported in nmol/L to ng/mL.
Vitamins
Can we enlist vitamin D to fight flu pandemic?
The piece sets out John Cannell's hypothesis that flu is a symptom of vitamin D deficiency. It notes his argument that most of the 36 children the CDC reported dying of H1N1 in 2009 had neurodevelopmental conditions, stayed indoors and took anticonvulsants, all worsening vitamin D status.
Vitamins
Vitamin D Newsletter: More letters
A Vitamin D Council newsletter reprinting a reader's letter to Dr. Cannell, from a 46-year-old who took 60,000 to 180,000 IU of vitamin D3 daily for about eight months, reached a blood level of 406 ng/mL with elevated calcium, and asks how to reverse the effects.
Cancer
New evidence: Vitamin D supplements reduce breast cancer risk
In a Canadian case-control study of 3,101 breast cancer patients and 3,471 controls, women taking 400 IU of vitamin D a day had 24 percent lower risk than non-users. Vitamin D from food showed no association, and calcium supplements were not significantly linked to risk.
Vitamins
Vitamin D Newsletter: Pseudomonas pneumonia
A reader's letter to the Vitamin D Council asking Dr. Cannell whether 30,000 IU a day is enough for her hospitalized 71-year-old mother with Pseudomonas pneumonia, with the opening of his reply.
Vitamins
Trial results show vitamin D helps prevent flu
In a randomized, double-blind trial of Japanese schoolchildren published in the American Journal of Clinical Nutrition, influenza A struck 10.8 percent of those taking 1,200 IU of vitamin D3 daily against 18.6 percent of controls, a 48 percent lower risk.
Vitamins
Vitamin D and Urinary Incontinence (press release)
Researchers at SUNY Upstate Medical University studied 1,961 women and found low vitamin D levels predicted pelvic floor disorders, with urinary incontinence twice as likely in deficient women. The authors suggest treating insufficiency could improve pelvic muscle strength.
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