A 2004 study of 115,096 Norwegian breast, colon and prostate cancer cases found patients diagnosed in summer and fall, when sun exposure and vitamin D3 levels run higher, were more likely to survive than those diagnosed in spring and winter.
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Vitamins
Research on vitamins A through K, deficiencies and supplementation.
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Vitamins
Vitamin C helps reduce complications from type 2 diabetes mellitus, slow the aging process
Researchers incubated glucose-spiked blood from diabetes patients for four weeks and found added vitamin C cut non-enzymatic glycation by 20 to 26 percent and the formation of advanced glycation end products by 26 to 28 percent versus controls.
Vitamins
Vitamin C helps prevent prostate cancer
A meta-analysis of 18 cohort and case-control studies covering 103,658 subjects tied vitamin C intake to lower prostate cancer risk, with 150 mg a day linked to 20% lower risk in case-control data. A 1997 lab study found vitamin C slowed prostate cancer cell growth.
Vitamins
Pollutants up insulin resistance risk, but vitamin C ---
In a trial of 141 elderly people randomly assigned vitamin C or placebo for four weeks, serum PFOS and PFDoDA tracked with higher HOMA insulin resistance scores, and vitamin C blunted that effect, suggesting the antioxidant offsets oxidative stress from the pollutants.
Vitamins
Vitamin C may protect against Alzheimer's disease
Older adults with thicker carotid intima-media, an indirect marker of vascular damage, tended to have lower vitamin C levels, while vitamins A and E and antioxidant enzymes showed weaker links. The authors suggest adequate vitamin C may matter for vascular and cognitive ageing.
Vitamins
Vitamin C protects against head and neck cancers
Pooled data from ten case-control studies, covering 5,959 cases and 12,248 controls, linked the highest quintile of vitamin C intake from food to 46 percent lower risk of oral and pharyngeal cancer and 48 percent lower laryngeal cancer risk. Whether supplements do the same is unknown.
Vitamins
Vitamin D fights colorectal cancer
A meta-analysis found colorectal cancer patients in the highest quintile of circulating 25-hydroxyvitamin D were 37 percent less likely to die during follow-up than those in the lowest. The authors suggest restoring deficient patients to a 30-80 ng/ml range.
Vitamins
Vitamin D fights hepatitis B
Among 426 people with chronic hepatitis B followed about 13 years, those deficient in vitamin D at baseline were 90 percent more likely to develop clinical events such as liver cancer, cirrhosis complications or death. Event rates were 25.5 percent with deficiency versus 11.1 percent without.
Vitamins
Vitamin D deficiency linked to worse hepatitis B outcomes
Among 426 chronic hepatitis B patients in Hong Kong followed about 159 months, 82% were vitamin D deficient at baseline, and those deficient were 90% more likely to develop liver cancer or cirrhosis complications or to die. Vitamin D was not tied to cirrhosis or viral load.
Vitamins
Vitamin k2 supplements prevent arterial stiffness, reduce cardiovascular risk
In a three-year trial, 244 healthy postmenopausal women took 180 ug of menaquinone-7 daily or placebo. Supplementation improved arterial stiffness, particularly among the women whose arteries were stiffest to begin with.
Vitamins
High dietary vitamin E or alpha-tocopherol prevents aggressive prostate cancer
Among 2,102 men with prostate cancer, European Americans in the highest quartile of dietary alpha-tocopherol intake were 66% less likely to have aggressive disease and African Americans 42% less likely. Adipose tissue tocopherol showed no significant association.
Vitamins
Sun exposure, vitamin D cuts risk of pancreatic cancer
Comparing cloud-adjusted UVB levels with pancreatic cancer rates, researchers found people in countries with low UVB exposure were six times more likely to develop the cancer than those in high-UVB countries, which they say is consistent with vitamin D playing a role.
Vitamins
Vitamin C may protect against Alzheimer's disease
Among older people with no or very mild cognitive impairment, plasma vitamin C and E ran lower in those with thicker carotid intima-media, but only vitamin C showed a dose-response. The authors say adequate vitamin C status might matter for protection against Alzheimer’s.
Vitamins
Vitamin D prevents colorectal cancer
Comparing 318 colon and rectal cancer cases with 624 matched controls from two US cohorts, researchers found high serum 25(OH)D correlated with a 90% lower risk of tumors showing a strong immune reaction, but no lower risk of tumors with weaker reaction.
Vitamins
Vitamin D supplements may fight colorectal cancer
Among 1,043 patients with metastatic colorectal cancer enrolled in a randomized treatment trial, those with the highest serum vitamin D levels survived a median of 32.6 months versus 24.5 months for those with the lowest, according to work set for the 2015 Gastrointestinal Cancers Symposium.
Vitamins
Vitamin D supplements help vitamin D deficient type 2 diabetes mellitus patients
In a double-blind trial of 81 type 2 diabetes patients with vitamin D of 10-30 ng/mL, 50,000 IU weekly for eight weeks normalized vitamin D and lowered fasting glucose, insulin and HOMA-IR but left adiponectin unchanged. The authors say eight weeks may have been too short.
Vitamins
Vitamin D may prevent some but not all sorts of influenza illness
In a Japanese trial, high school students taking 2,000 IU of vitamin D3 daily had about the same overall influenza A rate as those on placebo, 13.5 against 12.1 percent, during the 2009 H1N1 pandemic. The vitamin D group had fewer cases in month one but more in month two.
Vitamins
Vitamin C restores E coli endotoxin induced endothelial dysfunction
In a crossover trial, 36 men given E. coli endotoxin had flu-like symptoms, lower serum vitamin C and endothelial function cut by up to 76 percent. Two high intravenous doses of vitamin C, 320 and 480 mg/kg, restored endothelial function, the Vascular Pharmacology authors report.
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