In a six-month Iranian trial, patients with less than 50 percent coronary narrowing took 15.3 grams a day of Heracleum persicum fruit extract or placebo. The extract left cholesterol unchanged but significantly lowered triglycerides, which the authors call a possible adjunct treatment.
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Nutrition
Vitamins, minerals, supplements, herbs and diet: the research on how what we eat shapes our health.
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Supplements
Curcumin fights Alzheimer's disease
In APPswe/PS1dE9 mice, curcumin supplementation improved spatial learning and memory while reducing amyloid-beta aggregation, lowering presenilin-2 and raising amyloid-degrading enzymes, a Beijing University of Chinese Medicine team reports.
Vitamins
The Clinical Impact of Vitamin C: My Personal Experiences as a Physician
Cardiologist Thomas E. Levy recounts twenty years of using vitamin C, beginning with a visit to dentist Hal Huggins's Colorado Springs clinic that led him to close his cardiology practice. He gave 50-gram infusions to seriously ill patients undergoing extensive dental surgery.
Vitamins
Multivitamin, protein/amino acid supplements make you feel better
A survey of US military and Coast Guard personnel found users of multivitamin and protein or amino acid supplements reported feeling more awake, relaxed, cheerful and clearheaded. The authors caution the link may not be causal, citing no known biological mechanism.
Diet
Low carb diet better than low fat diet for weight loss?
Sixty people ate under 40 grams of carbohydrate a day and about sixty others kept fat under 30% of calories for 12 months. The low-carb group lost more weight and fat mass and did better on HDL and triglycerides. The writer notes what participants actually ate was not tracked.
Food
Low type 2 diabetes mellitus risk linked to high fiber cereal breakfast
Among 4,116 UK children aged 9 to 10, those who skipped breakfast had higher fasting insulin, insulin resistance, HbA1c, glucose and urate than daily breakfast eaters, and high-fibre cereal eaters had the lowest insulin resistance. The authors say trials are still needed.
Vitamins
Multivitamin helps diabetes mellitus
Rats given streptozotocin plus a multivitamin preparation for eight weeks improved on every diabetes measure taken, including fasting glucose, HbA1c, glucose tolerance and insulin, while males on the drug alone worsened. Female rats showed no benefit and no severe prediabetic phenotype.
Supplements
Micronutrient supplement fights chronic periodontitis in postmenopausal women
A pilot study from India found postmenopausal women with chronic periodontitis who took a micronutrient supplement alongside conventional treatment showed greater gains in superoxide dismutase activity and bigger drops in gingival inflammation and bleeding than treatment alone.
Supplements
Forskolin/rolipram supplements prevent obesity or weight again
Rats on a high-fat diet gained less weight when given forskolin or rolipram, and the two together worked better than either alone, a Turkish study found. Both raised serum cAMP and free fatty acid levels, which the authors tie to fat breakdown.
Vitamins
Coenzyme Q10 helps heart failure too
In a trial of 62 heart failure patients in Iran, adding 100 mg of coenzyme Q10 twice daily to 10 mg of atorvastatin for four months raised ejection fraction and improved New York Heart Association class compared with atorvastatin alone.
Supplements
Yacon root extract may help type 1 diabetes mellitus
In rats with drug-induced type 1 diabetes, an aqueous yacon root extract lowered food and water intake, blood glucose, total cholesterol, VLDL, LDL and triglycerides, and normalized ALT activity, which the researchers read as a possible liver-protective effect. The work is in rats.
Food
Sugar sweetened beverages linked to larger waist circumference
Drawing on 2,455 older children in the UK's Avon Longitudinal Study, researchers found those consuming the most sugar-sweetened beverages from age 10 to 13 had larger waist circumference, along with higher body mass index and total body fat mass.
Diet
Comment: The linoleic acid hazard
A reader challenges a WHO article on preventing cardiovascular disease as outdated, quoting Joseph Hibbeln on mouse studies where raising linoleic acid from 1% to 8% of calories tripled endocannabinoid levels and removing it stopped a 60%-fat diet from causing obesity.
Herbs
Herbal supplement helps osteoarthritis
In a one-week trial of 79 adults with mild-to-moderate knee osteoarthritis, the herbal supplement UP446, made from Scutellaria baicalensis and Acacia catechu extracts, reduced pain and improved knee range of motion. Both it and naproxen eased stiffness.
Diet
What to eat to improve insulin resistance
Carbohydrates are not the enemy in type 2 diabetes, an editor's note argues; high saturated fat, trans fat and protein intakes do the long-term harm. It points to a Mediterranean pattern, fat held under 30 percent and more fiber, with weight loss the most effective way to improve insulin resistance.
Diet
Lemon and walking fight high blood pressure
Japanese researchers asked 101 middle-aged women in Hiroshima to record their lemon intake and walking, and report that daily lemon and walking were effective against high blood pressure.
Diet
Amino acids/protein supplements may help IBS
A low-FODMAP diet eases bloating, abdominal pain and wind in irritable bowel syndrome, apparently by denying gut bacteria the fermentable carbohydrates they turn into gas. A further study finds those bacteria also make methylglyoxal, which the writer suggests may point to protein supplements.
Supplements
Supplements for Multiple sclerosis
A review reports up to 70 percent of multiple sclerosis patients have tried complementary treatments, and names a low-fat diet, omega-3 fatty acids, lipoic acid and vitamin D as the most promising, for their potential anti-inflammatory and neuroprotective effects.
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