A Mayo Clinic phase II trial in 42 patients found EGCG, a green tea compound, showed moderate clinical activity in stabilising chronic lymphocytic leukemia. An earlier phase I trial cut blood leukemia cells by about 20% in 30% of patients and halved swollen nodes in about 70%.
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Phytochemicals
Plant compounds such as flavonoids, carotenoids and polyphenols, and what they do.
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Phytochemicals
Resveratrol Boosts Brain Blood Flow
In a Northumbria University study reported in the American Journal of Clinical Nutrition, participants who took 250 or 500 milligrams of resveratrol showed a dose-dependent increase in blood flow to the brain. Mercola notes resveratrol can cross the blood-brain barrier.
Phytochemicals
Broccoli Component Limits Breast Cancer Stem Cells
Sulforaphane, a compound in broccoli, targeted and killed breast cancer stem cells and prevented new tumors in mice and cell cultures. Current chemotherapies do not work on these cells. Science Daily notes the concentrations used exceeded what eating broccoli provides.
Phytochemicals
Flavonoids rich foods reduce heart risk
Among 34,489 postmenopausal women followed 16 years in the Iowa Women's Health Study, higher anthocyanidin intake tracked with less coronary heart disease and lower total mortality, and top-quintile flavanone intake with 12 percent lower mortality. No link appeared for stroke deaths.
Phytochemicals
Green tea may be good for your eye
Rats given green tea absorbed catechins into the lens, retina and other eye tissue, where the compounds reduced oxidative stress for up to 20 hours, a Chinese University of Hong Kong study in the Journal of Agricultural and Food Chemistry found.
Phytochemicals
Culprit Compounds That Block Beans' Healthful Iron Probed
ARS physiologist Raymond Glahn and Cornell colleagues are tracing the compounds that block iron absorption from beans, following cell-culture work that flagged the polyphenol kaempferol as a likely culprit in red and pinto beans. Poultry trials now follow up that finding.
Phytochemicals
Could This 'Forbidden Medicine' Eliminate the Need for Drugs?
Amy Lansky defends homeopathy against a November 2009 American Journal of Medicine commentary by Michael Baum and Edzard Ernst, arguing they garble the terminology and lean on a single flawed meta-analysis while ignoring positive ones.
Phytochemicals
Mistletoe extract helps cancer survival
A systematic review in BMC Cancer pooled 41 studies of the mistletoe extract Iscador and put the overall hazard ratio for survival at 0.59. The authors flag considerable publication bias, and randomised studies showed weaker effects than non-randomised ones.
Phytochemicals
Cholesterol's Too High? Eat Lots of Veggies
In a placebo-controlled crossover feeding trial of 18 adults, 459 and 2,059 mg of dietary phytosterols a day raised fecal and biliary cholesterol excretion and cut intestinal absorption, and the 2,059 mg dose significantly lowered LDL cholesterol.
Phytochemicals
Drinking beer prevents prostate cancer?
A roundup of research on xanthohumol, a hops compound that slowed prostate cancer cell growth in culture and showed promise in rats. Researcher Emily Ho warns beer holds far too little, the effective dose matching about 17 beers, and that alcohol is a recognized human carcinogen.
Phytochemicals
Drinking green tea may help prevent hepatic fibrosis
Korean researchers report that green tea extract cut collagen deposition in a rat hepatic stellate cell line and prevented liver fibrosis in rats given a fibrosis-inducing chemical. They suggest it may warrant study as a treatment or preventive measure.
Phytochemicals
Green Tea Holds Promise for Treatment of Brain Disorders
Scientists found that pairing green tea's EGCG with a chemical called DAPH-12 can prevent and destroy amyloids, the tightly packed protein sheets implicated in Alzheimer's, Huntington's and Parkinson's diseases. Amyloids are highly stable and have resisted earlier attempts to break them down.
Phytochemicals
Green pigments may help prevent liver cancer
Linus Pauling Institute researchers found that chlorophyll and chlorophyllin each cut absorption of aflatoxin B, a potent liver carcinogen found in corn and peanuts, in a small group of Chinese volunteers, and helped clear the toxin faster in one or more subjects.
Phytochemicals
Pine bark improves circulation, swelling and visual acuity in early diabetic retinopathy (PR)
An Italian randomised trial of 46 diabetic patients, published in the Journal of Ocular Pharmacology and Therapeutics, reports that Pycnogenol, a French maritime pine bark extract, improved microcirculation, retinal swelling and visual acuity in early diabetic retinopathy.
Phytochemicals
Dietary polypenols may delay onset of Alzheimer’s disease
Mice fed a diet rich in polyphenols and polyunsaturated fatty acids grew more new cells in the olfactory bulb and hippocampus, both damaged in Alzheimer's, Spanish researchers report. They point to grapes, olive oil, cocoa, nuts, oily fish and soy beans as sources that may delay onset.
Phytochemicals
Green tea helps protect against hepatic fibrosis
In rats with chemically induced liver fibrosis, green tea extract curbed proliferation of activated hepatic stellate cells and reduced collagen deposition. The Korean researchers concluded green tea may protect liver cells and limit collagen buildup in the liver.
Phytochemicals
Curry Compound Kills Esophageal Cancer Cells
Curcumin, the yellow pigment in turmeric, began destroying cultured esophageal cancer cells within 24 hours in Cork Cancer Research Centre work published in the British Journal of Cancer. The cells died by a route different from the apoptosis other phytochemicals trigger.
Phytochemicals
Curry and turmeric help smokers with head and neck cancer
Researchers testing curcumin against head and neck squamous cell carcinoma cell lines found it blocked nicotine from activating cancer-causing cells, suggesting curry powder and turmeric might counter nicotine's effect in smokers. Presented at the 2009 AAO-HNSF meeting.
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