A UCLA-led team reports in Science Translational Medicine that vitamin D is needed for both innate and adaptive immune responses against the bacteria that cause tuberculosis. The researchers suggest melanin-rich skin, which makes less vitamin D, may partly explain higher susceptibility.
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Vitamin D
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Vitamins
The Wonder Vitamin That May Help You Prevent 16 Types of Cancer
Dr. Mercola interviews Carole Baggerly of GrassrootsHealth, who took up vitamin D research after her 2005 breast cancer diagnosis. He argues serum levels of 50 to 70 ng/ml could help prevent at least 16 types of cancer, citing over 200 epidemiological studies.
Vitamins
Vitamin C, vitamin D may help fight lung cancer
Taiwanese researchers implanted Lewis lung carcinoma in mice, then injected vitamin C and vitamin D combinations twice weekly for 28 days. They report dose-dependent suppression of tumour growth and spread, normalised body weight and lower plasma metalloproteinase activity.
Vitamins
Taking extremely high doses of vitamin D doesn't prevent falls and fractures in women
In a trial of 2,256 women averaging 76 years old, those given a single large oral dose of vitamin D3 each fall or winter were 15 percent more likely to fall and 26 percent more likely to fracture a bone than the placebo group, with the fall rate highest in the first three months.
Vitamins
Vitamin D reduces risk of breast cancer
A review of 11 case-control studies in Anticancer Research found women in the highest quartile of serum vitamin D were 39 percent less likely to be diagnosed with breast cancer than those in the lowest, and women at 47 ng/ml of 25-hydroxyvitamin D were 50 percent less likely.
Vitamins
Vitamin D linked to early menarche
Among 242 Colombian girls followed for 30 months, 57 percent of those deficient in vitamin D had reached menarche, against 23 percent of girls with sufficient levels. Deficient girls started about 0.8 years earlier and were twice as likely to have menarche early after adjustment.
Vitamins
Vitamin D levels appear to be associated with risk of skin cancer, although relationship is complex (PR)
Among 3,223 white HMO members studied at Henry Ford Hospital, higher vitamin D levels appeared to accompany higher risk of nonmelanoma skin cancer. The authors caution that UV exposure, which both creates vitamin D and causes skin cancer, complicates the relationship.
Diabetes
Got insulin resistance? Vitamin d supplements can help
In a six-month randomized trial of 81 South Asian women with insulin resistance, 4,000 IU of vitamin D a day raised average blood levels from 21 to 75 nmol/L and improved insulin sensitivity, with benefit maximized above 80 nmol/L. Insulin secretion was unaffected.
Vitamins
Depression linked to stroke, vitamin D may help both
Among 80,574 women in the Nurses' Health Study, those with a history of depression had 29% higher stroke risk over six years, and antidepressant users 39% higher; researchers suspect the drugs mark severity rather than cause strokes. The piece then floats vitamin D as a shared factor.
Vitamins
Low vitamin D linked to earlier first menstruation, a risk factor for health problems throughout life (PR)
University of Michigan researchers measured vitamin D in 242 girls aged 5 to 12 in Bogota, Colombia and followed them 30 months. Girls low in vitamin D were twice as likely to start menstruating during the study, which epidemiologist Eduardo Villamor ties to later health risks.
Vitamins
The Stunning Effect of This Single Vitamin on CANCER...
Mercola summarises Daniel Haley's book The Politics of Healing, which claims the FDA suppressed ten non-toxic cancer treatments, including Stanislaw Burzynski's, and accuses the agency of serving drug makers. He links this to whistleblower David Graham's 2004 testimony.
Cancer
Diet, breast density and breast cancer risk
Harvard researchers compared 1,042 postmenopausal women with breast cancer to 1,794 without and found those with 50% or more breast density had triple the risk of women below 10%. Denser breasts went with in situ, larger, estrogen-receptor-negative and higher-grade tumours.
Vitamins
Mushrooms contain vitamin d2, but not all mushrooms are the same
A Virginia Tech analysis found vitamin D2 varies widely by mushroom: 0.1-0.3 micrograms per 100 g in white button, crimini, portabella and enoki; 0.4-0.7 in shiitake and oyster; 5.2-28.1 in morel, chanterelle and maitake; and 3.4-20.9 in UV-treated portabella.
Vitamins
Vitamin D reduces risk of falls
Pooling 26 moderate-quality trials with 45,782 mostly elderly, mostly female participants, Mayo Clinic researchers found vitamin D use associated with a 14 percent lower risk of falls, strongest among those deficient at baseline or also taking calcium. The authors note data quality was not high.
Vitamins
Low serum vitamin D linked to higher death risk in breast cancer patients
Among 1,295 postmenopausal breast cancer patients followed 5.8 years, each 10 nmol/L drop in pre-chemotherapy serum vitamin D corresponded to 8% higher death risk and 14% higher distant recurrence risk. Samples taken after chemotherapy began showed no such link.
Vitamins
Vitamin D relieves pain induced by aromatase inhibitors in breast cancer patients
In a phase II trial of 60 breast cancer patients taking anastrozole, Washington University researchers gave high-dose vitamin D2 or placebo along with daily calcium, and found supplementation was associated with less joint and muscle pain.
Vitamins
Vitamin D Council Newsletter - Vitamin D and autism, cancer, and other health conditions
A Vitamin D Council newsletter in which Dr. Cannell answers readers' questions, including one from a mother whose son's autistic symptoms improved on vitamin D and whose pediatrician wants supplements stopped over a 25(OH)D level of 122.
Vitamins
Circumcision, vitamin D help prevent HIV infection
An International AIDS Society report on 110,000 adults in South Africa suggests circumcision may cut sexually transmitted HIV risk in men by 60%. The piece stresses this is an association rather than a trial and that condoms remain necessary, then raises vitamin D as a possible factor.
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