In preclinical models, the omega-3 fatty acid DHA curbed endometrial cancer cell proliferation, colony formation and migration in a dose- and time-dependent way, and promoted apoptosis. The researchers point to suppression of mTORC1 and mTORC2 signaling as the likely mechanism.
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Nutrition
Vitamins, minerals, supplements, herbs and diet: the research on how what we eat shapes our health.
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Vitamins
Taking B vitamins won't prevent Alzheimer's disease
Oxford researchers pooled 11 randomized trials covering 22,000 people and found B vitamins cut blood homocysteine by about a quarter but made no difference to memory, processing speed, executive function or overall cognition compared with placebo.
Diet
MedDiet has varied effects on cognitive decline among different races -- Ben-Gurion University researcher
Researchers analyzed eight years of Health ABC data on 2,326 adults aged 70 to 79 and found close adherence to a Mediterranean diet tracked with slower cognitive decline among African American but not white participants. They say other populations must be studied to confirm it.
Herbs
Dry ginger extract fights Alzheimer's disease
An ethanol extract of dry ginger showed high antioxidant activity, raised survival of rat hippocampal cells exposed to amyloid beta and blocked formation of amyloid beta oligomers, which the authors say suggests it may help prevent Alzheimer's disease.
Supplements
Fish oil supplements improve memory function
Rhode Island Hospital researchers found that older adults in the Alzheimer's Disease Neuroimaging Initiative who used fish oil supplements showed significantly slower cognitive decline and less brain atrophy. The retrospective study covered 819 participants.
Supplements
Lipoic acid helps circadian rhythms in elderly people, and more
Linus Pauling Institute researchers fed lab animals high doses of lipoic acid and found some age-related liver dysfunctions restored and circadian rhythm function improved. The dose matched about 600 mg a day for a 150-pound person, more than diet can supply.
Minerals
Zinc supplementation may help fight depression
Drawing on two Australian cohorts of people aged 50 to 85, a study found those with the highest zinc intake had a 30 to 50% lower risk of depression than those with the lowest. The writer cautions against zinc oxide supplements, which often use nanoparticles.
Food
Palm oil may induce anxiety?
Palmitic acid injected into mice produced anxiety-like behavior 24 hours later, without impairing locomotion, food intake, depressive-like behavior or spatial memory. The article adds that palm oil's saturated fat can also raise LDL cholesterol, limiting its value as a trans fat substitute.
Supplements
Omega 3 fatty acids help osteoarthritis
In mice on a high-fat diet, getting 8 percent of calories from omega-3 fats eased injury-induced osteoarthritis, improved wound repair and lowered leptin and resistin, while saturated and omega-6 fats worsened joint damage. The writer notes that dose equals about 20 grams a day for adults.
Nutrition
Multiple-Use Dental Dispenser Devices
Multiple-use dental dispensers deliver impression materials, adhesives and composites through disposable tips, but the body is stored and reused. CDC classes such devices as semicritical and calls for sterilizing them once contaminated, which would damage the material inside.
Supplements
American ginseng is safe to use to treat type 2 diabetes mellitus
In a 12-week double-blind trial of 74 people with well-controlled type 2 diabetes, 500 mg of American ginseng per meal left kidney, liver and hemostatic function unchanged from baseline, with no difference in the number or severity of adverse events versus placebo.
Diet
FDA Posts Updated Results for its Total Diet Study
The FDA posted Total Diet Study data for foods collected from 2006 to 2011, reporting arsenic, cadmium, lead and mercury plus 12 nutritional elements in about 280 table-ready foods. The agency found statistically significant declines in sodium in several processed foods.
Supplements
L-arginine supplements help type 2 diabetes mellitus
In diabetic rats, L-arginine supplementation preserved nitric oxide production, raised glomerular blood flow and filtration rate, and improved glucose tolerance. The authors say it may delay the onset of insulin resistance and renal dysfunction under hyperglycemic stress.
Minerals
Seaweed supplements help iodine deficiency
Combet and colleagues at the University of Glasgow report in the British Journal of Nutrition that low-level seaweed supplementation improved iodine status in iodine-insufficient women. They tie the shortfall to low intakes of dairy products and seafood in the UK and other European countries.
Diet
Do statins increase and Mediterranean diet decrease the risk of breast cancer?
De Lorgeril and Salen argue that a modernised Mediterranean diet — high omega-3 to omega-6 ratio, fibre, polyphenols, low-glycemic foods — lowers breast cancer risk, while statins have been associated with higher risk. They urge doctors to weigh such therapies in high-risk women.
Minerals
Calcium Makes for an Environmentally Friendly Pickle
ARS researchers in Raleigh, North Carolina found calcium chloride can replace most of the sodium chloride in pickle brine, keeping cucumbers firm and speeding fermentation, and leaving a spent solution usable as a soil amendment. Mt. Olive Pickle Company has adopted it.
Diet
Dietary factors and prostate cancer
A systematic review suggests red meat, dietary fat and milk may raise prostate cancer risk while fruit, vegetables and polyphenols may lower it. It says selenium and vitamin supplements should not be advocated for prevention, and high doses may even worsen prognosis.
Vitamins
Vitamin D3 supplements improve urticaria or hives
In a trial of 42 chronic urticaria patients already on triple drug therapy, adding 4,000 IU of vitamin D3 daily cut symptom scores a further 40 percent by week 12 while 600 IU did not. The high dose also tracked with better sleep and itch scores, with no adverse events.
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