Comparing 726 prostate cancer patients with 527 men without it, researchers linked hamburgers, processed meat, grilled red meat and well-done red meat to 79, 57, 63 and 52 percent higher risk of advanced, but not localized, disease. White meat showed no association.
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Prostate Cancer
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Food
Coffee may reduce the risk of deadly prostate cancer
Harvard's Kathryn Wilson and colleagues followed 47,911 men for 22 years and found those drinking six or more cups of coffee a day had a 20 percent lower risk of prostate cancer overall and a 60 percent lower risk of advanced disease. Regular and decaffeinated coffee both counted.
Vitamins
Vitamin D fights prostate cancer - new study
Among 841 men with prostate cancer, those whose tumors expressed vitamin D receptors most highly had lower PSA, Gleason score and stage, and were 83 percent less likely to have lethal disease. Blood vitamin D before diagnosis showed no such link.
Supplements
Omega-3 Fatty Acids Linked to Prostate Cancer Risk
Among 3,461 men in the Prostate Cancer Prevention Trial, those with the most DHA in their blood were two and a half times more likely to have aggressive prostate cancer, Fred Hutchinson researchers report, echoing the EPIC study. The piece lists other trials where fish oil showed no benefit.
Lifestyle
Acupuncture helps hot flashes in prostate cancer patients
Among 14 men treated for prostate cancer, twice-weekly acupuncture lowered an average hot flash score from 28.3 to 10.3 after four weeks and to 7 after eight, according to a study in the International Journal of Radiation Oncology. A randomized trial is being designed.
Vitamins
Study: Retinol tied to risk of prostate cancer
A National Cancer Institute study in the American Journal of Epidemiology linked the highest quintile of serum retinol to a 19 percent higher risk of prostate cancer, rising to 31 percent when two blood draws were combined. Whether retinol itself drives the disease is unknown.
Vitamins
Study explain why vitamin D protects against prostate cancer
Stanford researchers report that calcitriol, the active form of vitamin D, inhibits prostate cancer cell growth by acting on prostaglandin metabolism, suppressing the COX-2 gene and the EP2 and FP receptors. They propose pairing it with NSAIDs as a possible therapeutic strategy.
Lifestyle
Physical activity cuts risk of prostate cancer death
Harvard and UCSF researchers followed 2,705 men with prostate cancer for 18 years. Those doing vigorous activity beyond 180 minutes a week were 61% less likely to die of the disease, and walking 90 or more minutes at a brisk pace tracked with 46% lower all-cause mortality.
Disease
Pomegranate juice may help prevent prostate cancer
Pomegranate juice killed cultured prostate cancer cells and left the survivors sticking more and migrating less, UC Riverside researchers told a cell biology meeting. They identified the active compounds and planned animal tests of two of them.
Disease
Shorter index fingers linked to higher prostate cancer risk
Men whose index fingers were shorter than their ring fingers were about a third more likely to develop prostate cancer, and 87 percent more likely among men under 60, according to a British Journal of Cancer study. Relative finger length is set before birth.
Drug
Staging localized prostate cancer useless
Reviewing 3,875 registry cases, UCSF's Adam Reese found clinical stage assigned incorrectly 35% of the time, largely because physicians mishandled ultrasound and biopsy results. Even after the stages were corrected, stage showed no correlation with outcomes after radical prostatectomy.
Cancer
J&J Drug Provides Hope to Prostate Cancer Patients
In a Phase III trial of men with advanced prostate cancer who had already had other treatment, those given abiraterone with a low-dose steroid lived 14.8 months against 10.9 on placebo. Lead investigator Johan de Bono noted only four drugs have ever shown a survival benefit in the disease.
Cancer
Eating fish lowers risk of dying from prostate cancer
Reviewing 17 case-control and 14 cohort studies, Konrad Szymanski's team found no link between eating fish and getting prostate cancer, but heavy fish eaters were 44 percent less likely to develop metastatic disease and up to 63 percent less likely to die of it.
Drug
Prostate cancer patients may become impotent after surgery
A Spanish review found erectile dysfunction after prostate cancer surgery varied by technique: 22 percent with robotic surgery, 40 percent with laparoscopic and 41.4 percent with open radical prostatectomy. The underlying case series were rated low quality.
Nutrition
New Cases of Prostate Cancer by Race and Ethnicity
Prostate cancer is the most common cancer in US men but is more common in African-American men and less common in Hispanic, Asian, Pacific Islander and Native American men. In 2006, 203,415 men were diagnosed and 28,372 died; new cases fell 2.4% a year from 2000.
Drug
Prostate cancer screening no benefits for men with low PSA value
For men aged 55 to 74 with PSA levels below 2 ng/mL, 24,642 would need screening and 724 prostate cancers would need treating to prevent one death, an analysis of more than 86,000 men found. For men with levels between 10 and 19.9 ng/mL, 133 screenings would prevent one death.
Minerals
High selenium linked to lower risk of bladder cancer
A meta-analysis of studies from the US, Belgium, Finland and the Netherlands linked higher selenium in serum and toenails to as much as 39 percent lower bladder cancer risk. The effect showed up mainly in women, which researchers attribute to sex differences in how selenium accumulates.
Nutrition
Where can I learn about prostate or ovarian cancer?
September marks both National Prostate Cancer and National Ovarian Cancer Awareness Month. Using National Library of Medicine material, the post explains how tumors form and spread, then points to NCI, CDC and FTC resources and an FDA warning about online cancer fraud.
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