An Archives of Internal Medicine study of men diagnosed with prostate cancer between 2004 and 2006 found those with PSA under 4 were treated much like men with levels of 4 to 20. More than 70 percent of men below 20 ng/mL had their prostates removed or underwent radiation.
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Prostate Cancer
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Cancer
Mediterranean diet cuts prostate cancer risk
Reviewing evidence in Molecular Nutrition and Food Research, Itsiopoulos and University of Melbourne colleagues note that Greek men in Greece and in Australia die of prostate cancer less often than men in many Western countries, and suggest the Mediterranean diet may explain the gap.
Cancer
Swedish Study: PSA Screening Saves Lives
A University of Gothenburg study followed 20,000 men for 14 years and found prostate cancer deaths were half as high among those offered PSA screening. Critics point to overdiagnosis: one US study found that for every 20 men treated, only one benefits from early screening.
Cancer
Study: Soy and Brazil nuts fight prostate cancer
Genistein from soy and selenium from Brazil nuts, separately and together, slowed the growth of both hormone-dependent and hormone-independent prostate cancer cells and cut MMP-2 expression, with the combination most effective. Healthy prostate cells were unaffected.
Drug
Too many elderly men receive PSA testing - study
Among 9,000 U.S. men aged 76 or older with no prostate cancer history, 60 percent reported a PSA test in the past year, despite 2008 task force guidance against screening men 75 and older.
Disease
On the Father's Day, text message this to your dad
A Father's Day roundup of prostate cancer research: studies tied higher dairy intake, high-fat diets and three weekly drinks to greater risk, while regular exercise was linked to fewer diagnoses and pharmacological doses of vitamin C shrank tumors in rats.
Drug
No treatment needed for low-risk prostate cancer
Reuters reports on a Journal of the National Cancer Institute analysis pooling 10 studies of Swedish men: after 8 years, 20 percent of untreated men had died versus twice as many of the treated. The untreated men were actually sicker, and predicted 10-year deaths still favored watching.
Vitamins
Vitamin C fights prostate cancer - study
Rats implanted with hormone-refractory prostate cancer cells and given pharmacological doses of vitamin C by injection for 30 days had significantly smaller primary tumours and far fewer lung and lymph node metastases, researchers report in In Vivo.
Drug
Radiotherapy helps prostate cancer patients
In a Canadian trial of 1,200 men with prostate cancer severe enough to warrant hormone therapy, 74 percent of those given radiation alongside hormones were alive at seven years against 66 percent on hormones alone — an average gain of about six months.
Watch-List
Dairy products linked to high prostate cancer risk
A case-control study by Raimondi and colleagues in Prostate compared 197 men with prostate cancer and 197 controls in Montreal and found those eating more dairy were twice as likely to have the disease. Because it is not a trial, dairy cannot be called the cause.
Drug
Prostate cancer patients getting hormone therapy at risk of blood clots
A study of 76,000 Swedish men found younger patients on hormone therapy for prostate cancer were about two and a half times more likely to suffer deep-vein thrombosis and twice as likely to have a pulmonary embolism. Researchers say the link does not show the treatment caused clots.
Food
Walnuts Slow Prostate Tumors
Mice with prostate tumors that ate a walnut quantity a man could easily match showed controlled tumor growth and changes in genes governing tumor growth and metabolism. Walnuts supply omega-3 fats and antioxidants, and clinical studies link them to lower cardiovascular risk.
Diet
Walnuts and low fat diet may curb growth of prostate cancer
Prostate tumors grew slowly in mice fed a diet with 20 percent of calories from walnuts - about as slowly as on a 5 percent fat diet - while a 20 percent fat diet sped growth. Paul Davis says a man would need roughly 500 calories of walnut oil for a comparable effect.
Food
Drinking alcohol raises prostate cancer risk
Duke researchers told the Genitourinary Cancers Symposium that among 334 men undergoing prostate biopsy, those regularly having three alcoholic drinks a week were 2.46 times as likely as non-drinkers to develop prostate cancer. They point to acetaldehyde, a known carcinogen.
Diet
Not all types of fat have the same effect on prostate cancer risk
Feeding 80 xenografted mice either a 40-percent-fat western diet or a low-fat diet, Lloyd and colleagues found no difference in weight, survival, PSA or IGF measures. They argue in the Journal of Urology that the type of fat matters more than the amount.
Drug
Thinking to get prostate cancer screening? Give it second thought!
The American Cancer Society told doctors to discuss screening risks after two trials: one of 76,600 US men found no difference in prostate cancer deaths, while one of 182,000 European men found 20% fewer deaths but needed 48 men treated to prevent one.
Cancer
Louis Gossett diagnosed with prostate cancer
Louis Gossett Jr., 73, says he has early stage prostate cancer and went public to urge African-Americans to seek early examination and treatment. The piece notes men 70 and older are not advised to screen routinely, since diagnosis and treatment may do more harm than good.
Disease
Genetic mutations linked to prostate cancer prognosis
British researchers tested tumour samples from 308 patients for three genetic abnormalities. Patients with none of them often did well, 85 percent alive 11 years after diagnosis, while the roughly 6 percent who had lost PTEN without ERG or ETV1 rearrangement faced high risk of dying of their cancer.
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