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Prostate Cancer

Drug

Prostate cancer vaccine shows promise

A phase 2 trial of the Prostvac-VF vaccine in men with symptomatic castration-resistant metastatic prostate cancer reported a 44 percent lower death rate over three years, with 30 percent alive versus 17 percent of controls. One catch: vaccinated men averaged about four years younger.

Diet

Fat intake increases prostate cancer risk

Comparing 512 prostate cancer patients with 838 men without the disease, University of Nottingham researchers found the highest intakes of total, saturated, monounsaturated and polyunsaturated fat carried 2.3 to 2.7 times the risk of the lowest intakes.

Jan 24, 2010

Disease

Genetic Variant Linked to Deadly Prostate Cancer

Wake Forest researchers compared 4,849 men with aggressive prostate cancer to 12,205 with slow-growing disease and found the variant rs4054823 carried a 25 percent higher risk of aggressive disease. Coauthor Jianfeng Xu says a predictive panel test may be possible.

Jan 17, 2010

Phytochemicals

Drinking beer prevents prostate cancer?

A roundup of research on xanthohumol, a hops compound that slowed prostate cancer cell growth in culture and showed promise in rats. Researcher Emily Ho warns beer holds far too little, the effective dose matching about 17 beers, and that alcohol is a recognized human carcinogen.

Dec 13, 2009

Cancer

Don't count on coffee to fight prostate cancer

A roundup of short items on prostate cancer risk: exercise, sunlight and vitamin D, and green tea have each been linked to lower risk, red and processed meat to higher risk, and the piece calls coffee's reported benefit controversial.

Dec 9, 2009

Nutrition

Vitamin D may have an effect on prostate cancer

Researchers compared 122 prostate cancer patients with 130 matched controls in southern China and found one vitamin D receptor variant, BsmI, tracked with prostate cancer risk. They conclude such polymorphisms may be potential risk factors.

Dec 8, 2009

Cancer

Drinking coffee may lower advanced prostate cancer risk

Harvard researchers following 50,000 men found those who drank the most coffee were 60 percent less likely to develop aggressive prostate cancer than men who drank none. Caffeine showed no association, and which components might protect remains unknown.

Dec 8, 2009

Cancer

Obesity, dietary fats affect prostate cancer risk

In a study of 40 men aged 50 to 80, half with prostate cancer, BMI was higher among the patients but not significantly so, though it tracked with tumor aggressiveness. Their total, saturated and unsaturated fat intake was higher, and omega-3, vitamin C and lycopene intake lower.

Nov 8, 2009

Food

Red Meat, Processed Meats May Raise Prostate Cancer Risk

Following 174,343 US men for nine years, National Cancer Institute researchers recorded 10,313 prostate cancers and found the highest red meat intake carried 12 percent more total risk and 31 percent more advanced disease. Nitrite and nitrate tracked with 24 and 31 percent higher risk.

Nov 7, 2009

Lifestyle

Exercise Cuts Prostate Cancer Risk

Among 190 men biopsied for suspected prostate cancer, those walking the equivalent of three to six hours a week were two-thirds less likely to be diagnosed than sedentary men. The study shows an association, not that exercise caused the drop.

Nov 7, 2009

Lifestyle

Physical Activity Cuts Prostate Cancer Risk

Actor Dennis Hopper, 73, has been diagnosed with prostate cancer. The article pairs that news with a British Journal of Cancer study of 45,887 Swedish men, which found physical activity such as walking or bicycling was inversely associated with prostate cancer risk.

Nov 1, 2009

Disease

Andrew Lloyd Webber diagnosed with prostate cancer*

Media reports say the 61-year-old composer is being treated for early-stage disease and is expected back at work by year's end. Background follows on how the prostate works, the 192,280 US cases and 27,360 deaths projected for 2009, and known and suspected risk factors.

Oct 26, 2009

Nutrition

Do phytosterol reduce risk of heart disease? and more!

An AICR Q&A: 2 grams of phytosterols a day can lower LDL cholesterol about 10 percent in people with high cholesterol, though reaching that usually takes fortified products, and there is no known benefit at healthy levels. The writer knows of no research tying whey to prostate cancer.

Sep 13, 2009

Obesity

Obesity may raise prostate cancer risk

Brenda Hernandez and colleagues at the University of Hawaii tracked 83,879 men, 5,554 of whom developed prostate cancer, and found the effect of weight varied by ethnicity: being overweight in older adulthood raised risk among white and Native Hawaiian men but not Japanese men.

Sep 12, 2009

Disease

Retrovirus potential risk factor for prostate cancer

Utah and Columbia researchers found DNA from the retrovirus XMRV in 27 percent of more than 200 prostate cancers, against 6 percent of non-cancerous tissue, with viral proteins almost exclusively in malignant cells. If the link proves causal, tests and vaccines might follow.

Sep 7, 2009

Diet

How to prevent prostate cancer?

A roundup of earlier reports on diet and prostate cancer, covering plant-based diets, black tea, lycopene with soy isoflavones, and a Japanese study in which men drinking five or more cups of green tea a day were 48 percent less likely to develop advanced disease.

Sep 2, 2009

Obesity

Obesity linked to advanced prostate cancer

A Cancer Epidemiology, Biomarkers and Prevention study of 84,000 men by Brenda Hernandez found those overweight or obese in young adulthood faced higher risk of advanced prostate cancer. Because it is not a trial, it cannot show that obesity causes the added risk.

Sep 2, 2009

Diet

Does obesity raise prostate cancer risk?

Brenda Hernandez examined health data on 84,000 men and found those obese or overweight at 21 had lower risk of localized, low-grade prostate cancer, while heavy weight gain in young adulthood tracked with advanced, high-grade disease in white men.

Sep 1, 2009

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