In a trial reported in the Journal of Clinical Endocrinology and Metabolism, 52 men with low-risk prostate cancer took 4,000 IU of vitamin D3 daily for a year, and most of those who finished saw their Gleason scores fall. David Marshall's team tracked PSA every two months and rebiopsied.
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Supplements
Warren Buffet gets prostate cancer, study suggests green tea may help him
Korean researchers report in the International Journal of Molecular Medicine that the green tea catechins EC, EGC and EGCG triggered apoptosis in prostate cancer cells and suppressed androgen receptor activity. The piece also questions treating early prostate cancer in men over 70.
Vitamins
Do you know how to prevent lethal prostate cancer?
Among men in the Health Professionals Follow-up Study, those whose prediagnostic vitamin D was in the highest quartile were 57 percent less likely to develop lethal prostate cancer than those in the lowest. No significant link appeared with prostate cancer overall.
Supplements
These supplements fight prostate cancer
In mice carrying human prostate tumors, combining a soy diet with calcitriol inhibited tumor growth more than either alone but also caused hypercalcemia and in some cases lethal toxicity, a study in Prostate found. Soy raised the bioavailability of calcitriol.
Cancer
Cancer news: Whole walnuts may help prevent prostate cancer
Mice on a high-fat diet containing whole walnuts had slower prostate tumour growth and lower tumour weight than controls on soybean-oil diets, plus lower prostate weight, IGF-1, resistin and LDL at 18 weeks, across a 24-week feeding study.
Food
Beef, spam and sausage boost prostate cancer risk
The piece cautions that one Illinois man's recovery after proton therapy proves nothing, since many prostate cancers progress slowly and patients often survive untreated. It notes screening is not advised past age 70, because aggressive follow-up can do more harm, including loss of sexual function.
Cancer
Milk boosts prostate cancer risk, studies suggest
Following 8,894 Icelandic men for 24 years, Johanna Torfadottir's team found men who drank milk daily as teenagers but stopped later were three times as likely to be diagnosed with advanced prostate cancer. The study is observational and proves no cause.
Food
Dairy products may raise cancer risk
Oxford's Timothy Key reports that blood IGF-1 tracks with breast and prostate cancer risk and that high dairy protein intake raises IGF-1. He cites work linking five or more daily servings of dairy to a 65% higher prostate cancer risk.
Food
Eating broccoli and cauliflower cuts prostate cancer risk
Ben Liu's meta-analysis of seven cohort and six case-control studies found men eating cruciferous vegetables were 10% less likely to be diagnosed with prostate cancer. Cohort studies alone showed no significant link; case-control studies suggested up to 21%.
Supplements
Experts Warn: This Popular Vitamin can Trigger Cancer
Mercola disputes coverage of a trial reporting 17% higher prostate cancer risk among men taking 400 IU of vitamin E daily, arguing the trial used a synthetic, petrochemically derived form, and calls a study tying supplements to mortality in older women deeply flawed.
Vitamins
Vitamin E may boost risk of prostate cancer
In a trial of 35,533 men followed 7 to 12 years, those given 400 IU of vitamin E daily were 17 percent more likely to develop prostate cancer; selenium alone was linked to a 9 percent increase. The trial tested one form of vitamin E, not all of them.
Vitamins
Use of vitamin E associated with increased risk of prostate cancer (PR)
In SELECT, a trial of 35,533 men, those randomized to daily vitamin E supplements had a significantly increased risk of prostate cancer, JAMA reports. The trial's first report had found no risk reduction from vitamin E or selenium and a statistically nonsignificant rise with vitamin E.
Food
High intake of calcium, dairy products boosts prostate cancer risk
A review links high calcium intake from food and supplements to advanced or fatal prostate cancer. Among 783 black men, those reporting the highest calcium intake were twice as likely to have localized and advanced disease, and genotype appeared to shape how much the risk rose.
Lifestyle
Current smokers with prostate cancer more likely to die early
Among 5,366 men with prostate cancer in the Health Professionals Follow-up Study, those smoking at diagnosis were 61 percent more likely to die of the disease and to see it recur. After adjustment the increases were 38 and 47 percent, and rose with pack-years. Published in JAMA.
Drug
Take acetaminophen to prevent prostate cancer? Not so fast!
An American Cancer Society study tied taking more than 30 acetaminophen pills a month for five years or more to a 38 percent lower risk of prostate cancer, though it was observational. A separate study of 64,839 adults suggests heavy use may double blood-cancer risk.
Drug
Take acetaminophen to prevent prostate cancer? Not so fast!
An American Cancer Society study links taking more than 30 acetaminophen pills a month for five years or more to 38 percent lower prostate cancer risk, 51 percent for aggressive disease. The piece pairs it with work in 64,839 adults suggesting heavy use may double the risk of some blood cancers.
Disease
Acetaminophen linked to lower risk of prostate cancer
Among 78,000 men in the Cancer Prevention Study II cohort, those taking more than 30 acetaminophen pills a month for five years or longer had about 38 percent lower overall prostate cancer risk and 51 percent lower risk of aggressive disease. Shorter use showed no reduction.
Vitamins
Vitamin D may help cut risk of death from prostate cancer
Among 1,822 men with prostate cancer, those whose pre-diagnosis 25(OH)D was in the lowest quartile were 59 percent more likely to die of the disease and 22 percent more likely to die of any cause than men with the highest levels. The active form 1,25(OH)2D showed no link.
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